TRPV1

GENERAL INFORMATION

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Gene name

TRPV1

Gene description

Transient receptor potential cation channel, subfamily V, member 1

Protein class

Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Not detected

Protein evidence

Evidence at transcript level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Not detected

Organ

Expression



GENE INFORMATION

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Gene name

TRPV1 (HGNC Symbol)

Synonyms

VR1

Description

Transient receptor potential cation channel, subfamily V, member 1 (HGNC Symbol)

Entrez gene summary

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p13.2

Chromosome location (bp)

3565444 - 3597098

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000196689 (version 78.38)

Entrez gene

7442

UniProt

neXtProt

Antibodypedia

TRPV1 antibodies


PROTEIN BROWSER

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ENST00000310522
 
ENST00000399756
 
ENST00000399759
 
ENST00000425167
 
ENST00000571088
 
ENST00000576351
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRPV1-001 ENSP00000461007
ENST00000571088
Q8IZY9
Show all »
Show » Show » 839 95 No 6
TRPV1-002 ENSP00000382661
ENST00000399759
Q8IZY9
Show all »
Show » Show » 839 95 No 6
TRPV1-003 ENSP00000382659
ENST00000399756
Q8IZY9
Show all »
Show » Show » 839 95 No 6
TRPV1-004 ENSP00000459042
ENST00000576351
I3L1R6
Show all »
Show » Show » 829 93.9 No 6
TRPV1-005 ENSP00000409627
ENST00000425167
E7EQ78
Show all »
Show » Show » 850 96.1 No 6
TRPV1-006 ENSP00000311692
ENST00000310522
E7ESJ2
Show all »
Show » Show » 779 88.1 No 6