FAN1

GENERAL INFORMATION

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Gene name

FAN1

Gene description

FANCD2/FANCI-associated nuclease 1

Protein class

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Subsets of cells in lymphoid tissues and of astrocytes in CNS showed moderate cytoplasmic positivity. Remaining normal tissues were mainly negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA041383
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

FAN1 (HGNC Symbol)

Synonyms

KIAA1018, MTMR15

Description

FANCD2/FANCI-associated nuclease 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the myotubularin-related class 1 cysteine-based protein tyrosine phosphatases. The encoded protein may be catalytically inactive. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2009]

Chromosome

15

Cytoband

q13.3

Chromosome location (bp)

30903852 - 30943108

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198690 (version 78.38)

Entrez gene

22909

UniProt

Q9Y2M0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y2M0

Antibodypedia

FAN1 antibodies


PROTEIN BROWSER

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ENST00000362065
 
ENST00000561594
 
ENST00000561607
 
ENST00000562892
 
ENST00000565466
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAN1-001 ENSP00000354497
ENST00000362065
Q9Y2M0
Show all »
Show » Show » 1017 114.2 No 0
FAN1-002 ENSP00000455983
ENST00000561594
Q9Y2M0
Show all »
Show » Show » 533 59.5 No 0
FAN1-003 ENSP00000454223
ENST00000561607
Q9Y2M0
Show all »
Show » Show » 533 59.5 No 0
FAN1-004 ENSP00000454544
ENST00000565466
Q9Y2M0
Show all »
Show » Show » 533 59.5 No 0
FAN1-008 ENSP00000457680
ENST00000562892
H3BUK3
Show all »
Show » 105 12 No 0