CDC42BPB

GENERAL INFORMATION

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Gene name

CDC42BPB

Gene description

CDC42 binding protein kinase beta (DMPK-like)

Protein class

Cytoskeleton related proteins
Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues displayed weak to moderate cytoplasmic immunoreactivity. Decidual cells and gall bladder showed strong cytoplasmic staining.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA022821
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

CDC42BPB (HGNC Symbol)

Synonyms

KIAA1124, MRCKB

Description

CDC42 binding protein kinase beta (DMPK-like) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q32.32

Chromosome location (bp)

102932379 - 103057462

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198752 (version 78.38)

Entrez gene

9578

UniProt

Q9Y5S2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5S2

Antibodypedia

CDC42BPB antibodies


PROTEIN BROWSER

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ENST00000361246
 
ENST00000558867
 
ENST00000559043
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDC42BPB-001 ENSP00000355237
ENST00000361246
Q9Y5S2
Show all »
Show » Show » 1711 194.3 No 0
CDC42BPB-002 ENSP00000453384
ENST00000559043
Q86TR8
Show all »
Show » Show » 667 74.5 No 0
CDC42BPB-004 ENSP00000453311
ENST00000558867
Show » Show » 212 23.2 No 0