DCAF12L1

GENERAL INFORMATION

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Gene name

DCAF12L1

Gene description

DDB1 and CUL4 associated factor 12-like 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (fallopian tube, testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic and membranous expression in e.g. ciliated cells of fallopian tube and glandular cells of the gastrointestinal tract.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation. Caution, targets protein from more than one gene.

Data reliability

Uncertain based on 3 antibodies.
HPA044737 , HPA048981 , HPA053138
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (fallopian tube, testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

DCAF12L1 (HGNC Symbol)

Synonyms

KIAA1892L, WDR40B

Description

DDB1 and CUL4 associated factor 12-like 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

q25

Chromosome location (bp)

126549383 - 126552851

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198889 (version 78.38)

Entrez gene

139170

UniProt

Q5VU92 (UniProt - Evidence at transcript level)

neXtProt

NX_Q5VU92

Antibodypedia

DCAF12L1 antibodies


PROTEIN BROWSER

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ENST00000371126
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DCAF12L1-001 ENSP00000360167
ENST00000371126
Q5VU92
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