The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Subsets of pancreatic islet cells, prostate glands and neuronal cells displayed strong cytoplasmic immunoreactivity. Epididymis and fallopian tube showed strong membranous staining. Thyroid, endometrial glands, cells in seminiferus ducts and endocervical gland were moderately stained. Remaining normal cells were mainly negative.
Most normal tissues showed moderate cytoplasmic positivity with additional membranous and/or nuclear staining in several cases. Strong cytoplasmic and luminal membranous positivity was observed in gastrointestinal glands. Hepatocytes and renal glomeruli showed strong cytoplasmic staining. Glial cells, lymphoid tissues, breast, heart and smooth muscle were weakly stained or negative.