ARHGEF38

GENERAL INFORMATION

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Gene name

ARHGEF38

Gene description

Rho guanine nucleotide exchange factor (GEF) 38

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (prostate)
GTEx:Tissue enhanced (prostate)

Protein evidence

Evidence at protein level

Protein localization

Weak to moderate cytoplasmic and occasional membranous positivity was observed in most of the normal tissues. Pancreatic islets, lung macrophages, breast and myocytes as well as basal cells in prostate, squamous and respiratory epithelium and showed strong staining. Cilia in bronchus and fallopian tubes were distinctly stained. The liver, alveolar cells, trophoblastic cells, glial cells and spleen were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA036510
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (prostate)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (prostate)

Organ

Expression



GENE INFORMATION

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Gene name

ARHGEF38 (HGNC Symbol)

Synonyms

FLJ20184

Description

Rho guanine nucleotide exchange factor (GEF) 38 (HGNC Symbol)

Entrez gene summary

Chromosome

4

Cytoband

q24

Chromosome location (bp)

105552620 - 105708093

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000236699 (version 78.38)

Entrez gene

54848

UniProt

Q9NXL2 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9NXL2

Antibodypedia

ARHGEF38 antibodies


PROTEIN BROWSER

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ENST00000265154
 
ENST00000420470
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGEF38-001 ENSP00000416125
ENST00000420470
Q9NXL2
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Show » Show » 777 89.1 No 0
ARHGEF38-004 ENSP00000265154
ENST00000265154
Q9NXL2
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Show » Show » 219 25.5 No 0