2027 GENES FOUNDi

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Gene

 

 

Gene description

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Protein class

x

 

 

 

 

Tissue

Cell

Cancer

 

 

 

 

 

 

Subcellular location

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RNA tissue category

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ALKAnaplastic lymphoma receptor tyrosine kinaseCancer-related genes
CD markers
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Plasma membraneTissue enhanced
PTPN20Protein tyrosine phosphatase, non-receptor type 20Enzymes
Predicted intracellular proteins
Microtubule organizing centerTissue enhanced
CENPECentromere protein E, 312kDaDisease related genes
Plasma proteins
Predicted intracellular proteins
Microtubules
Cytosol
Mixed
SMC2Structural maintenance of chromosomes 2Predicted intracellular proteins
Nucleus
Nucleoli
Mixed
TOP2ATopoisomerase (DNA) II alphaCancer-related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Nucleus
Nucleoli
Tissue enhanced
NCAPD3Non-SMC condensin II complex, subunit D3Plasma proteins
Predicted intracellular proteins
NucleoplasmTissue enriched
BRCA1Breast cancer 1, early onsetCancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Mixed
IFT20Intraflagellar transport 20Predicted intracellular proteins
MicrotubulesExpressed in all
MLH1MutL homolog 1Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
NucleoplasmExpressed in all
SGOL1Shugoshin-like 1 (S. pombe)Disease related genes
Predicted intracellular proteins
Tissue enhanced
BIRC5Baculoviral IAP repeat containing 5Cancer-related genes
Predicted intracellular proteins
Cytokinetic bridgeTissue enhanced
BUB1BUB1 mitotic checkpoint serine/threonine kinaseEnzymes
Predicted intracellular proteins
Nucleoplasm
Cytosol
Tissue enhanced
NDC80NDC80 kinetochore complex componentPredicted intracellular proteins
Nucleoplasm
Centrosome
Mixed
RBMXRNA binding motif protein, X-linkedCancer-related genes
Plasma proteins
Predicted intracellular proteins
NucleoplasmExpressed in all
SMC4Structural maintenance of chromosomes 4Plasma proteins
Predicted intracellular proteins
Nuclear speckles
Cytosol
Mixed
AURKBAurora kinase BCancer-related genes
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Nucleoplasm
Midbody
Tissue enhanced
C20orf173Chromosome 20 open reading frame 173Predicted intracellular proteins
Tissue enriched
C20orf194Chromosome 20 open reading frame 194Predicted intracellular proteins
Nucleoli fibrillar center
Mitochondria
Cytosol
Expressed in all
C3orf20Chromosome 3 open reading frame 20Predicted intracellular proteins
Tissue enriched
SMC1AStructural maintenance of chromosomes 1ACancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Cytosol
Expressed in all
MRE11AMRE11 homolog A, double strand break repair nucleaseCancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
NucleoplasmExpressed in all
AURKAAurora kinase ACancer-related genes
Enzymes
Plasma proteins
Predicted intracellular proteins
Nucleus
Centrosome
Cytosol
Tissue enhanced
BUB1BBUB1 mitotic checkpoint serine/threonine kinase BCancer-related genes
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
CytosolTissue enhanced
CENPACentromere protein APredicted intracellular proteins
NucleusTissue enhanced
CHTF8Chromosome transmission fidelity factor 8Predicted intracellular proteins
Predicted secreted proteins
NucleoplasmExpressed in all
NSL1NSL1, MIS12 kinetochore complex componentPredicted intracellular proteins
Nucleoplasm
Nuclear speckles
Cytosol
Expressed in all
POT1Protection of telomeres 1Cancer-related genes
Disease related genes
Predicted intracellular proteins
NucleusMixed
RAD21RAD21 cohesin complex componentCancer-related genes
Disease related genes
Predicted intracellular proteins
NucleoplasmExpressed in all
REC8REC8 meiotic recombination proteinPlasma proteins
Predicted intracellular proteins
NucleoplasmTissue enhanced
SPO11SPO11 meiotic protein covalently bound to DSBPlasma proteins
Predicted intracellular proteins
Tissue enriched
TOP1Topoisomerase (DNA) ICancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Nucleus
Nucleoli fibrillar center
Expressed in all
ESPL1Extra spindle pole bodies like 1, separaseEnzymes
Predicted intracellular proteins
Predicted membrane proteins
Nucleoplasm
Vesicles
Tissue enhanced
C20orf202Chromosome 20 open reading frame 202Predicted intracellular proteins
Tissue enhanced
CENPTCentromere protein TPredicted intracellular proteins
Nuclear bodiesExpressed in all
FAAP20Fanconi anemia core complex associated protein 20Predicted intracellular proteins
Nucleoplasm
Nuclear bodies
Cell Junctions
Expressed in all
SMC1BStructural maintenance of chromosomes 1BPredicted intracellular proteins
Nucleoplasm
Cytosol
Tissue enriched
DMC1DNA meiotic recombinase 1Predicted intracellular proteins
NucleoplasmTissue enriched
ACDAdrenocortical dysplasia homolog (mouse)Predicted intracellular proteins
Nuclear bodiesMixed
BRD4Bromodomain containing 4Cancer-related genes
Disease related genes
Predicted intracellular proteins
NucleoplasmExpressed in all
CDC20Cell division cycle 20Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Cytosol
Tissue enhanced
CDK2Cyclin-dependent kinase 2Cancer-related genes
Enzymes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Centrosome
Cytosol
Expressed in all
CENPCCentromere protein CPredicted intracellular proteins
Nucleoplasm
Nuclear bodies
Cytosol
Mixed
CENPFCentromere protein F, 350/400kDaCancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
NucleoplasmTissue enhanced
CENPMCentromere protein MPredicted intracellular proteins
CytosolTissue enhanced
CHTF18Chromosome transmission fidelity factor 18Predicted intracellular proteins
Nucleoplasm
Cytosol
Mixed
H2AFYH2A histone family, member YPlasma proteins
Predicted intracellular proteins
NucleusExpressed in all
HORMAD1HORMA domain containing 1Predicted intracellular proteins
NucleoplasmTissue enriched
KIF2CKinesin family member 2CCancer-related genes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Centrosome
Tissue enriched
KIF4AKinesin family member 4APredicted intracellular proteins
Nucleoplasm
Cytokinetic bridge
Mixed
KRT20Keratin 20, type IPlasma proteins
Predicted intracellular proteins
CytosolTissue enhanced

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