MRPL20

GENERAL INFORMATION

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Gene name

MRPL20

Gene description

Mitochondrial ribosomal protein L20

Protein class

Mitochondrial proteins
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression with a granular pattern.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA047074
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MRPL20 (HGNC Symbol)

Synonyms

FLJ10024

Description

Mitochondrial ribosomal protein L20 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.33

Chromosome location (bp)

1401908 - 1407313

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000242485 (version 78.38)

Entrez gene

55052

UniProt

Q9BYC9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BYC9

Antibodypedia

MRPL20 antibodies


PROTEIN BROWSER

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ENST00000344843
 
ENST00000482352
 
ENST00000492508
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL20-001 ENSP00000341082
ENST00000344843
Q9BYC9
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Show » Show » 149 17.4 No 0
MRPL20-003 ENSP00000460924
ENST00000482352
Q9BYC9
Show all »
Show » Show » 155 18.1 No 0
MRPL20-004 ENSP00000459994
ENST00000492508
I3L2X1
Show all »
Show » Show » 66 7.6 No 0