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BETA
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:294.0 nTPM
HPA Brain:233.9 nTPM
GTEx:294.0 nTPM
FANTOM5:507.1 Scaled Tags Per Million
Macaque:190.0 nTPM
Mouse:144.2 nTPM
Rat:169.4 nTPM
Pig:367.9 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 80
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 610
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

233.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 212.6
1870 Female, age 42, unknown 256.9
2411 Female, age 72, unknown 229.5
1833 Male, age 53, unknown 229.2
1830 Male, age 51, unknown 225.3
2666 Male, age 74, left hemisphere 219.9
2828 Female, age 72, unknown 218.4
2019 Male, age 18, unknown 215.3
1827 Male, age 72, unknown 210.0
2219 Male, age 76, both hemispheres 164.4
2586 Male, age 75, left hemisphere 157.0
Dorsal raphe nucleus
nTPM: 223.0
2016 Female, age 72, unknown 243.4
2750 Male, age 76, both hemispheres 230.8
2298 Female, age 72, unknown 225.4
1828 Male, age 53, unknown 214.1
2047 Male, age 72, unknown 201.2
Inferior colliculus
nTPM: 188.3
2097 Female, age 72, unknown 196.4
1848 Female, age 42, unknown 192.4
1890 Male, age 53, unknown 188.8
2849 Male, age 72, unknown 175.4
Median raphe nucleus
nTPM: 220.5
2220 Male, age 76, midline 220.5
Periaquaductal grey, anterior
nTPM: 202.6
1947 Male, age 18, unknown 213.9
2502 Female, age 75, unknown 203.2
1795 Male, age 51, unknown 190.6
Periaquaductal grey, dorsal
nTPM: 212.8
2850 Male, age 76, both hemispheres 251.3
1831 Male, age 72, unknown 215.0
2464 Female, age 72, unknown 196.3
1840 Male, age 53, unknown 188.8
Periaquaductal grey, lateral
nTPM: 204.6
2140 Male, age 76, both hemispheres 209.2
2053 Male, age 18, unknown 209.0
2272 Male, age 74, both hemispheres 195.6
Pretectal area
nTPM: 204.6
1815 Male, age 53, unknown 228.4
2224 Female, age 72, unknown 223.4
2667 Female, age 75, unknown 220.6
1817 Female, age 42, unknown 218.8
2316 Male, age 76, right hemisphere 214.2
2273 Male, age 74, both hemispheres 201.3
2825 Male, age 18, unknown 196.5
1944 Female, age 72, unknown 195.6
2007 Male, age 72, unknown 190.6
1816 Male, age 51, unknown 189.4
2407 Male, age 75, both hemispheres 171.4
Red nucleus
nTPM: 233.9
1821 Female, age 72, unknown 285.5
1904 Male, age 53, unknown 268.3
1954 Female, age 42, unknown 261.6
1865 Male, age 51, unknown 257.1
2503 Female, age 72, unknown 244.2
2823 Male, age 76, right hemisphere 241.7
2227 Male, age 72, unknown 232.8
2769 Male, age 72, unknown 229.9
2725 Female, age 75, unknown 228.8
2785 Male, age 18, unknown 216.2
2588 Male, age 74, left hemisphere 184.7
2584 Male, age 75, left hemisphere 156.6
Substantia nigra
nTPM: 225.6
2699 Male, age 18, unknown 248.2
1851 Male, age 51, unknown 242.3
2241 Male, age 72, unknown 233.4
1916 Female, age 42, unknown 233.1
2665 Male, age 74, both hemispheres 229.5
1889 Female, age 72, unknown 227.7
2409 Female, age 72, unknown 224.2
2590 Female, age 75, unknown 218.4
1941 Male, age 53, unknown 207.0
2583 Male, age 75, right hemisphere 191.8
Superior colliculus
nTPM: 205.7
1913 Female, age 42, unknown 272.8
1995 Male, age 72, unknown 244.9
2587 Male, age 74, left hemisphere 231.8
1839 Male, age 51, unknown 201.1
2668 Female, age 75, unknown 194.9
1796 Male, age 53, unknown 187.5
2087 Female, age 72, unknown 187.1
2261 Male, age 18, unknown 185.2
1895 Male, age 76, right hemisphere 183.5
2664 Male, age 75, both hemispheres 168.2
Ventral tegmental area
nTPM: 230.1
2223 Female, age 72, unknown 254.5
2410 Female, age 72, unknown 241.5
1915 Female, age 42, unknown 228.9
2218 Male, age 76, both hemispheres 226.5
2021 Male, age 53, unknown 222.1
1942 Male, age 51, unknown 207.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

294.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 294.0
Samples: 183

Max nTPM: 538.0
Min nTPM: 147.1
Std nTPM: 65.9
Median nTPM: 292.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 538.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 458.1
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 455.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 446.9
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 441.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 434.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 431.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 427.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 418.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 407.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 406.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 400.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 392.4
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 392.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 390.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 388.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 383.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 381.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 378.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 376.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 375.4
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 374.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 372.9
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 371.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 370.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 370.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 365.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 361.0
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 355.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 353.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 351.6
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 351.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 351.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 348.7
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 348.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 348.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 347.9
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 346.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 345.5
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 344.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 344.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 343.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 343.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 340.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 339.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 338.1
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 334.6
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 329.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 329.2
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 328.2
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 327.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 325.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 324.2
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 320.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 317.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 317.5
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 317.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 317.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 315.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 314.8
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 314.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 312.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 311.2
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 310.7
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 310.4
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 309.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 307.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 306.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 306.5
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 306.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 305.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 304.8
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 303.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 303.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 302.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 302.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 300.7
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 300.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 299.5
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 299.2
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 299.2
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 298.8
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 297.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 296.5
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 296.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 295.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 294.2
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 294.2
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 294.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 294.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 293.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 292.9
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 292.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 292.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 292.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 292.0
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 290.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 288.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 288.6
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 288.0
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 287.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 287.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 283.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 279.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 278.6
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 277.8
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 277.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 277.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 277.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 276.0
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 275.5
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 272.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 271.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 269.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 267.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 266.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 265.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 264.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 263.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 262.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 262.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 261.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 261.3
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 261.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 260.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 259.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 258.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 256.2
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 255.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 254.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 253.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 252.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 250.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 249.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 246.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 246.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 245.9
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 245.9
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 245.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 245.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 245.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 244.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 243.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 243.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 243.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 242.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 239.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 239.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 237.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 237.1
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 234.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 231.4
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 231.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 229.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 227.8
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 225.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 223.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 220.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 220.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 218.9
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 217.9
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 216.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 216.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 214.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 213.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 212.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 211.3
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 206.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 206.4
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 206.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 203.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 203.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 203.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 199.8
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 198.7
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 197.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 188.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 182.5
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 174.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 173.2
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 158.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 148.2
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 147.1
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

507.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 507.1
FF:10158-103A5 76 years, female 507.1

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

190.0
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 190.0
Samples: 1

Max nTPM: 190.0
Min nTPM: 190.0
Sample A 190.0
Midbrain
nTPM: 145.5
Samples: 1

Max nTPM: 145.5
Min nTPM: 145.5
Sample A 145.5
Superior colliculi
nTPM: 137.4
Samples: 1

Max nTPM: 137.4
Min nTPM: 137.4
Sample A 137.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

367.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 367.9
Samples: 3

Max nTPM: 420.7
Min nTPM: 338.4
Sample A Female 420.7
Sample B Female 338.4
Sample C Male 344.5
Midbrain
nTPM: 282.8
Samples: 3

Max nTPM: 353.1
Min nTPM: 234.5
Sample B Female 353.1
Sample C Male 260.9
Sample D Male 234.5
Periaqueductal gray
nTPM: 298.5
Samples: 3

Max nTPM: 304.6
Min nTPM: 288.6
Sample B Female 302.2
Sample C Male 304.6
Sample D Male 288.6
Superior colliculi
nTPM: 355.7
Samples: 4

Max nTPM: 392.8
Min nTPM: 317.9
Sample A Female 392.8
Sample B Female 386.6
Sample C Male 317.9
Sample D Male 325.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

144.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 144.2
Samples: 4

Max nTPM: 149.0
Min nTPM: 140.1
Sample A 145.3
Sample B 140.1
Sample C 142.3
Sample D 149.0

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

169.4
Rat sample Sample description nTPM
Midbrain
nTPM: 169.4
Samples: 4

Max nTPM: 173.7
Min nTPM: 166.7
Sample A 166.7
Sample A 173.7
Sample A 170.5
Sample A 166.7

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