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BETA
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  • DYNLL1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
Brain proteome
Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:677.5 nTPM
HPA Brain:360.2 nTPM
GTEx:677.5 nTPM
FANTOM5:556.5 Scaled Tags Per Million
Macaque:312.6 nTPM
Mouse:100.2 nTPM
Rat:276.4 nTPM
Pig:196.3 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 440
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 490
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

360.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 259.1
2411 Female, age 72, unknown 363.2
1870 Female, age 42, unknown 341.6
1833 Male, age 53, unknown 295.8
1827 Male, age 72, unknown 284.9
1830 Male, age 51, unknown 270.3
2019 Male, age 18, unknown 236.5
2828 Female, age 72, unknown 229.6
2219 Male, age 76, both hemispheres 229.1
2586 Male, age 75, left hemisphere 177.0
2666 Male, age 74, left hemisphere 162.7
Dorsal raphe nucleus
nTPM: 358.8
2298 Female, age 72, unknown 486.4
2047 Male, age 72, unknown 377.4
2750 Male, age 76, both hemispheres 319.4
1828 Male, age 53, unknown 306.9
2016 Female, age 72, unknown 303.8
Inferior colliculus
nTPM: 291.0
2097 Female, age 72, unknown 317.8
2849 Male, age 72, unknown 308.6
1848 Female, age 42, unknown 290.0
1890 Male, age 53, unknown 247.4
Median raphe nucleus
nTPM: 344.7
2220 Male, age 76, midline 344.7
Periaquaductal grey, anterior
nTPM: 288.8
1947 Male, age 18, unknown 317.3
1795 Male, age 51, unknown 278.8
2502 Female, age 75, unknown 270.3
Periaquaductal grey, dorsal
nTPM: 318.3
2850 Male, age 76, both hemispheres 386.9
1840 Male, age 53, unknown 352.6
2464 Female, age 72, unknown 278.9
1831 Male, age 72, unknown 254.9
Periaquaductal grey, lateral
nTPM: 360.2
2272 Male, age 74, both hemispheres 438.1
2140 Male, age 76, both hemispheres 324.9
2053 Male, age 18, unknown 317.5
Pretectal area
nTPM: 301.8
2273 Male, age 74, both hemispheres 470.6
2224 Female, age 72, unknown 368.3
2667 Female, age 75, unknown 316.6
2825 Male, age 18, unknown 316.3
1817 Female, age 42, unknown 277.1
1944 Female, age 72, unknown 275.5
1815 Male, age 53, unknown 272.0
1816 Male, age 51, unknown 263.8
2007 Male, age 72, unknown 262.0
2407 Male, age 75, both hemispheres 255.0
2316 Male, age 76, right hemisphere 242.6
Red nucleus
nTPM: 252.6
1821 Female, age 72, unknown 335.0
2725 Female, age 75, unknown 293.6
1954 Female, age 42, unknown 270.2
1865 Male, age 51, unknown 263.3
2503 Female, age 72, unknown 256.4
1904 Male, age 53, unknown 254.0
2227 Male, age 72, unknown 249.5
2769 Male, age 72, unknown 248.2
2823 Male, age 76, right hemisphere 240.9
2785 Male, age 18, unknown 239.0
2584 Male, age 75, left hemisphere 191.8
2588 Male, age 74, left hemisphere 188.6
Substantia nigra
nTPM: 279.2
1916 Female, age 42, unknown 336.3
1941 Male, age 53, unknown 329.9
2241 Male, age 72, unknown 323.0
1889 Female, age 72, unknown 317.9
1851 Male, age 51, unknown 313.6
2699 Male, age 18, unknown 287.5
2409 Female, age 72, unknown 257.1
2590 Female, age 75, unknown 237.9
2583 Male, age 75, right hemisphere 201.2
2665 Male, age 74, both hemispheres 187.3
Superior colliculus
nTPM: 271.0
2587 Male, age 74, left hemisphere 361.0
1895 Male, age 76, right hemisphere 290.0
1796 Male, age 53, unknown 285.1
1913 Female, age 42, unknown 276.1
1839 Male, age 51, unknown 275.3
2261 Male, age 18, unknown 271.1
2668 Female, age 75, unknown 262.1
1995 Male, age 72, unknown 247.1
2087 Female, age 72, unknown 230.7
2664 Male, age 75, both hemispheres 211.5
Ventral tegmental area
nTPM: 307.4
2410 Female, age 72, unknown 351.9
2223 Female, age 72, unknown 342.1
1915 Female, age 42, unknown 312.9
2218 Male, age 76, both hemispheres 310.8
1942 Male, age 51, unknown 266.4
2021 Male, age 53, unknown 260.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

677.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 677.5
Samples: 183

Max nTPM: 1731.0
Min nTPM: 242.9
Std nTPM: 207.6
Median nTPM: 641.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1731.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1542.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1402.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1344.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1286.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1175.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1116.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1098.3
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 1094.7
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 1080.3
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 1046.3
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 1029.5
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 1020.4
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 1001.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 941.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 938.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 903.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 902.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 897.0
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 890.8
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 870.9
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 865.0
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 850.3
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 845.2
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 842.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 835.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 833.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 832.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 828.9
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 822.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 818.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 804.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 803.2
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 801.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 798.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 794.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 788.2
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 781.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 780.3
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 778.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 775.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 764.0
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 763.3
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 762.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 758.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 757.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 754.0
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 750.1
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 748.8
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 739.2
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 739.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 734.3
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 733.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 733.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 731.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 710.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 709.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 708.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 705.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 704.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 701.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 698.4
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 696.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 694.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 694.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 692.7
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 689.4
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 686.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 685.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 678.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 675.5
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 675.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 674.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 673.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 670.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 670.0
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 669.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 668.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 668.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 668.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 665.7
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 662.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 657.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 657.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 655.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 655.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 654.5
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 653.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 645.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 643.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 642.5
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 641.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 638.6
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 635.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 633.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 632.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 630.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 627.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 627.4
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 626.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 625.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 624.0
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 622.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 620.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 620.1
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 618.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 618.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 615.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 615.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 611.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 610.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 610.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 607.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 605.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 604.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 603.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 602.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 602.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 597.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 597.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 594.9
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 594.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 593.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 588.3
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 584.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 582.2
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 580.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 579.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 575.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 575.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 574.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 568.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 567.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 566.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 564.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 562.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 561.3
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 560.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 559.8
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 554.0
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 553.7
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 549.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 547.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 538.8
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 538.7
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 534.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 529.2
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 527.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 527.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 525.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 523.5
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 511.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 510.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 510.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 507.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 502.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 498.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 498.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 497.3
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 496.8
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 494.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 489.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 485.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 479.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 474.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 471.9
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 460.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 459.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 451.4
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 450.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 446.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 436.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 433.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 432.5
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 426.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 401.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 394.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 391.3
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 378.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 372.8
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 367.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 268.5
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 242.9
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

556.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 556.5
FF:10158-103A5 76 years, female 556.5

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

312.6
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 214.7
Samples: 1

Max nTPM: 214.7
Min nTPM: 214.7
Sample A 214.7
Midbrain
nTPM: 312.6
Samples: 1

Max nTPM: 312.6
Min nTPM: 312.6
Sample A 312.6
Superior colliculi
nTPM: 223.7
Samples: 1

Max nTPM: 223.7
Min nTPM: 223.7
Sample A 223.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

196.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 196.3
Samples: 3

Max nTPM: 247.4
Min nTPM: 163.9
Sample A Female 247.4
Sample B Female 163.9
Sample C Male 177.5
Midbrain
nTPM: 165.5
Samples: 3

Max nTPM: 176.1
Min nTPM: 155.8
Sample B Female 176.1
Sample C Male 155.8
Sample D Male 164.6
Periaqueductal gray
nTPM: 183.4
Samples: 3

Max nTPM: 205.5
Min nTPM: 158.1
Sample B Female 158.1
Sample C Male 186.6
Sample D Male 205.5
Superior colliculi
nTPM: 189.0
Samples: 4

Max nTPM: 229.0
Min nTPM: 155.8
Sample A Female 229.0
Sample B Female 155.8
Sample C Male 184.6
Sample D Male 186.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

100.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 100.2
Samples: 4

Max nTPM: 103.2
Min nTPM: 98.6
Sample A 100.1
Sample B 98.6
Sample C 98.9
Sample D 103.2

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

276.4
Rat sample Sample description nTPM
Midbrain
nTPM: 276.4
Samples: 4

Max nTPM: 286.4
Min nTPM: 267.8
Sample A 269.2
Sample A 282.3
Sample A 286.4
Sample A 267.8

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