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  • DPYSL2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:167.4 nTPM
HPA Brain:978.0 nTPM
GTEx:167.4 nTPM
FANTOM5:1152.9 Scaled Tags Per Million
Macaque:526.2 nTPM
Mouse:371.3 nTPM
Rat:432.4 nTPM
Pig:715.7 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 550
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 930
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

978.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 959.4
1870 Female, age 42, unknown 1077.2
2411 Female, age 72, unknown 1056.7
2586 Male, age 75, left hemisphere 1048.9
2828 Female, age 72, unknown 1024.6
1830 Male, age 51, unknown 980.0
1833 Male, age 53, unknown 972.8
1827 Male, age 72, unknown 955.3
2019 Male, age 18, unknown 898.2
2666 Male, age 74, left hemisphere 823.9
2219 Male, age 76, both hemispheres 756.6
Dorsal raphe nucleus
nTPM: 861.6
2750 Male, age 76, both hemispheres 1032.9
2047 Male, age 72, unknown 842.4
1828 Male, age 53, unknown 824.7
2298 Female, age 72, unknown 810.8
2016 Female, age 72, unknown 797.3
Inferior colliculus
nTPM: 758.3
1848 Female, age 42, unknown 806.7
2097 Female, age 72, unknown 777.9
2849 Male, age 72, unknown 769.1
1890 Male, age 53, unknown 679.6
Median raphe nucleus
nTPM: 886.7
2220 Male, age 76, midline 886.7
Periaquaductal grey, anterior
nTPM: 959.9
2502 Female, age 75, unknown 1031.9
1947 Male, age 18, unknown 999.6
1795 Male, age 51, unknown 848.1
Periaquaductal grey, dorsal
nTPM: 750.1
2850 Male, age 76, both hemispheres 786.9
2464 Female, age 72, unknown 776.8
1840 Male, age 53, unknown 719.6
1831 Male, age 72, unknown 717.2
Periaquaductal grey, lateral
nTPM: 874.3
2272 Male, age 74, both hemispheres 902.6
2053 Male, age 18, unknown 887.8
2140 Male, age 76, both hemispheres 832.6
Pretectal area
nTPM: 862.3
2273 Male, age 74, both hemispheres 957.0
2316 Male, age 76, right hemisphere 937.5
2407 Male, age 75, both hemispheres 927.1
1815 Male, age 53, unknown 878.6
2825 Male, age 18, unknown 876.7
2667 Female, age 75, unknown 862.8
1817 Female, age 42, unknown 830.2
2007 Male, age 72, unknown 829.7
2224 Female, age 72, unknown 816.9
1816 Male, age 51, unknown 797.8
1944 Female, age 72, unknown 770.9
Red nucleus
nTPM: 978.0
1865 Male, age 51, unknown 1087.2
1821 Female, age 72, unknown 1063.3
2503 Female, age 72, unknown 1046.0
1904 Male, age 53, unknown 1034.5
2725 Female, age 75, unknown 1028.6
2227 Male, age 72, unknown 1012.5
2769 Male, age 72, unknown 1009.6
1954 Female, age 42, unknown 968.5
2785 Male, age 18, unknown 958.1
2823 Male, age 76, right hemisphere 882.8
2588 Male, age 74, left hemisphere 864.7
2584 Male, age 75, left hemisphere 779.9
Substantia nigra
nTPM: 868.7
1916 Female, age 42, unknown 1082.5
1851 Male, age 51, unknown 1015.6
1941 Male, age 53, unknown 998.4
1889 Female, age 72, unknown 858.5
2241 Male, age 72, unknown 851.2
2590 Female, age 75, unknown 850.0
2699 Male, age 18, unknown 840.3
2409 Female, age 72, unknown 824.9
2583 Male, age 75, right hemisphere 773.9
2665 Male, age 74, both hemispheres 592.1
Superior colliculus
nTPM: 913.8
2664 Male, age 75, both hemispheres 1043.0
1913 Female, age 42, unknown 1022.6
2587 Male, age 74, left hemisphere 953.3
2261 Male, age 18, unknown 927.6
1995 Male, age 72, unknown 922.8
1796 Male, age 53, unknown 921.0
1839 Male, age 51, unknown 898.0
1895 Male, age 76, right hemisphere 860.9
2668 Female, age 75, unknown 804.2
2087 Female, age 72, unknown 784.7
Ventral tegmental area
nTPM: 926.4
2410 Female, age 72, unknown 1028.5
2223 Female, age 72, unknown 974.1
1915 Female, age 42, unknown 940.5
2218 Male, age 76, both hemispheres 920.4
2021 Male, age 53, unknown 855.8
1942 Male, age 51, unknown 839.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

167.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 167.4
Samples: 183

Max nTPM: 341.6
Min nTPM: 69.1
Std nTPM: 42.7
Median nTPM: 162.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 341.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 312.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 280.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 279.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 269.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 262.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 259.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 247.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 246.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 242.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 238.1
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 233.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 229.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 229.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 229.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 226.4
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 224.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 223.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 221.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 220.6
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 220.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 219.3
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 217.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 217.4
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 214.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 213.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 213.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 211.4
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 210.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 210.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 209.2
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 205.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 204.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 204.0
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 202.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 202.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 202.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 202.5
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 202.2
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 201.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 199.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 196.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 195.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 194.7
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 194.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 193.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 192.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 192.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 189.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 188.3
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 186.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 185.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 184.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 184.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 184.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 183.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 183.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 183.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 182.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 181.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 180.3
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 178.5
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 178.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 177.4
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 177.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 176.1
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 176.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 175.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 174.3
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 173.2
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 173.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 172.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 171.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 171.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 171.0
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 170.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 169.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 168.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 168.3
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 167.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 167.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 165.3
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 165.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 164.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 164.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 164.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 163.6
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 162.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 162.2
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 162.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 162.1
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 162.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 158.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 158.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 158.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 157.9
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 157.9
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 157.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 157.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 157.1
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 156.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 156.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 156.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 155.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 155.7
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 154.7
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 153.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 152.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 152.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 151.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 151.3
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 151.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 151.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 149.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 148.5
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 148.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 146.1
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 145.3
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 144.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 144.2
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 144.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 143.4
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 142.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 142.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 141.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 141.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 141.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 140.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 140.7
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 138.8
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 138.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 137.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 136.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 136.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 136.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 136.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 136.2
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 136.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 136.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 135.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 135.0
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 133.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 132.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 132.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 131.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 131.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 130.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 130.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 129.5
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 128.8
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 128.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 127.1
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 127.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 127.0
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 126.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 126.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 126.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 126.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 124.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 124.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 124.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 124.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 124.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 124.1
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 124.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 122.4
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 122.1
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 119.5
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 119.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 119.1
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 117.6
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 115.4
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 114.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 112.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 111.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 110.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 107.7
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 107.5
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 105.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 104.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 85.6
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 82.5
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 69.1
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1152.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1152.9
FF:10158-103A5 76 years, female 1152.9

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

526.2
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 494.8
Samples: 1

Max nTPM: 494.8
Min nTPM: 494.8
Sample A 494.8
Midbrain
nTPM: 430.7
Samples: 1

Max nTPM: 430.7
Min nTPM: 430.7
Sample A 430.7
Superior colliculi
nTPM: 526.2
Samples: 1

Max nTPM: 526.2
Min nTPM: 526.2
Sample A 526.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

715.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 715.7
Samples: 3

Max nTPM: 853.0
Min nTPM: 507.1
Sample A Female 853.0
Sample B Female 507.1
Sample C Male 787.0
Midbrain
nTPM: 645.8
Samples: 3

Max nTPM: 676.8
Min nTPM: 591.0
Sample B Female 669.7
Sample C Male 676.8
Sample D Male 591.0
Periaqueductal gray
nTPM: 591.0
Samples: 3

Max nTPM: 614.3
Min nTPM: 553.3
Sample B Female 605.5
Sample C Male 614.3
Sample D Male 553.3
Superior colliculi
nTPM: 638.1
Samples: 4

Max nTPM: 750.1
Min nTPM: 369.2
Sample A Female 697.8
Sample B Female 369.2
Sample C Male 735.1
Sample D Male 750.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

371.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 371.3
Samples: 4

Max nTPM: 383.4
Min nTPM: 343.0
Sample A 343.0
Sample B 375.8
Sample C 383.4
Sample D 383.2

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

432.4
Rat sample Sample description nTPM
Midbrain
nTPM: 432.4
Samples: 4

Max nTPM: 469.7
Min nTPM: 407.6
Sample A 407.6
Sample A 469.7
Sample A 440.7
Sample A 411.5

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