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  • HSP90AB1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:551.9 nTPM
HPA Brain:853.8 nTPM
GTEx:551.9 nTPM
FANTOM5:1958.7 Scaled Tags Per Million
Macaque:613.5 nTPM
Mouse:881.5 nTPM
Pig:661.6 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 800
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 870
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

853.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 623.9
2666 Male, age 74, left hemisphere 748.6
2411 Female, age 72, unknown 747.1
1827 Male, age 72, unknown 738.4
2219 Male, age 76, both hemispheres 664.9
2019 Male, age 18, unknown 595.7
1870 Female, age 42, unknown 594.0
1833 Male, age 53, unknown 580.0
2828 Female, age 72, unknown 567.5
1830 Male, age 51, unknown 514.6
2586 Male, age 75, left hemisphere 488.4
Dorsal raphe nucleus
nTPM: 739.0
2298 Female, age 72, unknown 916.8
2047 Male, age 72, unknown 843.5
1828 Male, age 53, unknown 715.6
2750 Male, age 76, both hemispheres 663.5
2016 Female, age 72, unknown 555.8
Inferior colliculus
nTPM: 566.4
2097 Female, age 72, unknown 627.1
2849 Male, age 72, unknown 553.8
1848 Female, age 42, unknown 546.7
1890 Male, age 53, unknown 537.8
Median raphe nucleus
nTPM: 853.8
2220 Male, age 76, midline 853.8
Periaquaductal grey, anterior
nTPM: 707.0
1947 Male, age 18, unknown 808.2
1795 Male, age 51, unknown 676.2
2502 Female, age 75, unknown 636.4
Periaquaductal grey, dorsal
nTPM: 596.1
1840 Male, age 53, unknown 654.7
2850 Male, age 76, both hemispheres 624.4
2464 Female, age 72, unknown 560.7
1831 Male, age 72, unknown 544.7
Periaquaductal grey, lateral
nTPM: 579.0
2272 Male, age 74, both hemispheres 629.8
2053 Male, age 18, unknown 564.4
2140 Male, age 76, both hemispheres 543.0
Pretectal area
nTPM: 681.4
1816 Male, age 51, unknown 877.6
2007 Male, age 72, unknown 769.9
1944 Female, age 72, unknown 769.7
1817 Female, age 42, unknown 749.1
2224 Female, age 72, unknown 725.3
1815 Male, age 53, unknown 691.3
2667 Female, age 75, unknown 688.5
2825 Male, age 18, unknown 614.1
2273 Male, age 74, both hemispheres 582.9
2407 Male, age 75, both hemispheres 552.8
2316 Male, age 76, right hemisphere 474.6
Red nucleus
nTPM: 587.9
1821 Female, age 72, unknown 752.7
2725 Female, age 75, unknown 716.3
2588 Male, age 74, left hemisphere 623.7
2503 Female, age 72, unknown 606.9
2584 Male, age 75, left hemisphere 585.8
1954 Female, age 42, unknown 569.4
1904 Male, age 53, unknown 555.7
1865 Male, age 51, unknown 549.4
2785 Male, age 18, unknown 546.9
2227 Male, age 72, unknown 524.3
2769 Male, age 72, unknown 522.1
2823 Male, age 76, right hemisphere 501.8
Substantia nigra
nTPM: 848.4
1916 Female, age 42, unknown 1205.9
1851 Male, age 51, unknown 984.1
2241 Male, age 72, unknown 975.9
1941 Male, age 53, unknown 940.9
1889 Female, age 72, unknown 798.2
2409 Female, age 72, unknown 786.0
2699 Male, age 18, unknown 777.4
2665 Male, age 74, both hemispheres 762.3
2590 Female, age 75, unknown 661.2
2583 Male, age 75, right hemisphere 591.8
Superior colliculus
nTPM: 581.1
2087 Female, age 72, unknown 670.6
2261 Male, age 18, unknown 663.3
1796 Male, age 53, unknown 662.8
2587 Male, age 74, left hemisphere 644.6
2668 Female, age 75, unknown 635.6
1839 Male, age 51, unknown 566.3
1895 Male, age 76, right hemisphere 542.6
2664 Male, age 75, both hemispheres 513.1
1913 Female, age 42, unknown 484.2
1995 Male, age 72, unknown 427.5
Ventral tegmental area
nTPM: 764.2
2410 Female, age 72, unknown 943.2
1915 Female, age 42, unknown 891.3
2218 Male, age 76, both hemispheres 823.5
2223 Female, age 72, unknown 661.5
1942 Male, age 51, unknown 656.1
2021 Male, age 53, unknown 609.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

551.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 551.9
Samples: 183

Max nTPM: 1833.4
Min nTPM: 240.8
Std nTPM: 235.1
Median nTPM: 478.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1833.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1256.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1175.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1152.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1148.9
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 1146.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1102.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1089.4
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 1082.3
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 1072.9
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 1019.3
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 1009.9
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 989.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 984.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 974.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 966.6
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 935.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 923.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 897.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 885.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 872.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 871.4
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 865.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 843.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 828.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 827.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 783.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 754.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 743.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 742.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 735.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 734.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 730.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 718.0
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 710.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 692.3
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 673.0
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 666.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 663.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 661.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 660.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 649.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 648.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 645.8
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 641.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 634.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 632.5
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 612.0
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 611.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 608.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 606.0
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 597.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 596.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 593.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 583.4
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 580.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 574.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 574.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 570.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 570.9
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 568.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 564.5
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 560.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 558.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 557.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 556.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 555.2
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 553.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 552.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 542.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 538.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 508.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 506.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 502.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 500.9
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 500.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 498.8
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 497.7
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 497.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 493.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 491.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 489.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 489.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 487.5
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 484.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 483.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 483.2
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 483.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 482.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 482.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 482.4
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 478.9
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 478.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 476.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 476.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 474.4
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 472.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 472.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 471.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 467.3
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 466.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 463.0
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 462.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 461.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 454.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 451.7
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 450.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 448.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 447.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 444.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 444.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 443.7
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 441.9
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 439.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 437.4
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 437.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 430.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 428.2
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 426.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 426.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 425.3
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 419.9
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 419.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 417.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 410.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 410.7
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 409.3
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 408.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 404.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 401.4
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 400.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 399.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 398.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 398.2
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 396.5
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 395.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 394.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 394.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 394.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 390.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 387.5
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 385.4
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 380.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 380.1
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 379.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 374.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 373.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 371.7
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 371.4
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 370.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 370.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 368.5
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 367.3
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 365.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 364.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 364.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 363.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 356.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 353.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 352.4
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 352.2
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 347.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 346.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 344.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 343.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 342.9
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 342.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 342.0
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 336.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 334.3
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 330.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 330.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 327.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 323.3
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 319.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 316.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 315.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 303.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 300.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 298.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 294.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 281.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 240.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1958.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1958.7
FF:10158-103A5 76 years, female 1958.7

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

613.5
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 613.5
Samples: 1

Max nTPM: 613.5
Min nTPM: 613.5
Sample A 613.5
Midbrain
nTPM: 515.2
Samples: 1

Max nTPM: 515.2
Min nTPM: 515.2
Sample A 515.2
Superior colliculi
nTPM: 482.0
Samples: 1

Max nTPM: 482.0
Min nTPM: 482.0
Sample A 482.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

661.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 661.6
Samples: 3

Max nTPM: 771.9
Min nTPM: 457.6
Sample A Female 755.3
Sample B Female 457.6
Sample C Male 771.9
Midbrain
nTPM: 582.8
Samples: 3

Max nTPM: 703.2
Min nTPM: 514.2
Sample B Female 514.2
Sample C Male 703.2
Sample D Male 531.0
Periaqueductal gray
nTPM: 478.3
Samples: 3

Max nTPM: 584.0
Min nTPM: 399.2
Sample B Female 451.7
Sample C Male 584.0
Sample D Male 399.2
Superior colliculi
nTPM: 541.0
Samples: 4

Max nTPM: 640.0
Min nTPM: 387.0
Sample A Female 603.5
Sample B Female 387.0
Sample C Male 640.0
Sample D Male 533.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

881.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 881.5
Samples: 4

Max nTPM: 902.2
Min nTPM: 827.3
Sample A 827.3
Sample B 902.2
Sample C 897.7
Sample D 898.8

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