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  • GFAP
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
PRIMARY MOUSE DATA
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:7623.8 nTPM
HPA Brain:16300.0 nTPM
GTEx:7623.8 nTPM
FANTOM5:5108.1 Scaled Tags Per Million
Macaque:2175.4 nTPM
Mouse:298.5 nTPM
Rat:292.6 nTPM
Pig:6303.5 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 10
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 2470
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16300.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 7929.5
2828 Female, age 72, unknown 14518.2
2666 Male, age 74, left hemisphere 10884.5
2586 Male, age 75, left hemisphere 9496.3
1870 Female, age 42, unknown 9090.4
1827 Male, age 72, unknown 8944.9
2411 Female, age 72, unknown 7536.3
1833 Male, age 53, unknown 6252.1
1830 Male, age 51, unknown 5734.4
2219 Male, age 76, both hemispheres 3720.4
2019 Male, age 18, unknown 3117.8
Dorsal raphe nucleus
nTPM: 12145.0
2016 Female, age 72, unknown 18348.4
2298 Female, age 72, unknown 12799.3
2047 Male, age 72, unknown 12300.2
1828 Male, age 53, unknown 11858.7
2750 Male, age 76, both hemispheres 5418.7
Inferior colliculus
nTPM: 9662.3
2849 Male, age 72, unknown 11137.4
2097 Female, age 72, unknown 10058.0
1848 Female, age 42, unknown 9859.6
1890 Male, age 53, unknown 7594.4
Median raphe nucleus
nTPM: 6723.0
2220 Male, age 76, midline 6723.0
Periaquaductal grey, anterior
nTPM: 10016.1
1795 Male, age 51, unknown 13214.2
2502 Female, age 75, unknown 9626.8
1947 Male, age 18, unknown 7207.3
Periaquaductal grey, dorsal
nTPM: 13836.4
1840 Male, age 53, unknown 16084.0
2850 Male, age 76, both hemispheres 14838.9
1831 Male, age 72, unknown 13206.9
2464 Female, age 72, unknown 11215.8
Periaquaductal grey, lateral
nTPM: 16300.0
2053 Male, age 18, unknown 25375.7
2140 Male, age 76, both hemispheres 14469.0
2272 Male, age 74, both hemispheres 9055.4
Pretectal area
nTPM: 7984.1
2825 Male, age 18, unknown 14204.2
2273 Male, age 74, both hemispheres 11615.3
2224 Female, age 72, unknown 9816.9
2316 Male, age 76, right hemisphere 9249.1
2407 Male, age 75, both hemispheres 8405.9
1944 Female, age 72, unknown 7847.1
2667 Female, age 75, unknown 6669.0
1815 Male, age 53, unknown 6514.7
1816 Male, age 51, unknown 5277.7
1817 Female, age 42, unknown 4455.1
2007 Male, age 72, unknown 3770.2
Red nucleus
nTPM: 6267.4
2503 Female, age 72, unknown 10517.7
2725 Female, age 75, unknown 7500.9
2769 Male, age 72, unknown 7370.3
2227 Male, age 72, unknown 6924.8
2823 Male, age 76, right hemisphere 6019.7
1821 Female, age 72, unknown 5960.0
2584 Male, age 75, left hemisphere 5632.1
2588 Male, age 74, left hemisphere 5535.0
1865 Male, age 51, unknown 5481.2
1954 Female, age 42, unknown 5413.5
1904 Male, age 53, unknown 5156.7
2785 Male, age 18, unknown 3697.1
Substantia nigra
nTPM: 7149.4
2699 Male, age 18, unknown 13372.5
1851 Male, age 51, unknown 7903.5
2590 Female, age 75, unknown 7638.7
2583 Male, age 75, right hemisphere 6905.1
1941 Male, age 53, unknown 6685.5
2665 Male, age 74, both hemispheres 6552.2
1916 Female, age 42, unknown 6291.1
1889 Female, age 72, unknown 5867.3
2409 Female, age 72, unknown 5864.2
2241 Male, age 72, unknown 4413.7
Superior colliculus
nTPM: 9751.1
1995 Male, age 72, unknown 13799.7
1913 Female, age 42, unknown 13070.3
2664 Male, age 75, both hemispheres 11656.4
1796 Male, age 53, unknown 11133.8
2587 Male, age 74, left hemisphere 9791.2
1839 Male, age 51, unknown 9186.8
2087 Female, age 72, unknown 8486.8
2668 Female, age 75, unknown 7690.4
2261 Male, age 18, unknown 7606.6
1895 Male, age 76, right hemisphere 5089.2
Ventral tegmental area
nTPM: 9943.4
2021 Male, age 53, unknown 13157.5
1915 Female, age 42, unknown 12611.8
1942 Male, age 51, unknown 12246.6
2223 Female, age 72, unknown 7622.6
2410 Female, age 72, unknown 7454.2
2218 Male, age 76, both hemispheres 6567.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

7623.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 7623.8
Samples: 183

Max nTPM: 26488.4
Min nTPM: 572.2
Std nTPM: 4184.7
Median nTPM: 6805.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 26488.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 20489.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 19425.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 19345.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 18859.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 16682.8
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 15800.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 15213.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 15078.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 14891.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 14608.8
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 14493.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 13994.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 13979.1
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 13810.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 13651.0
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 13613.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 13497.6
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 13392.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 13325.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 13224.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 13107.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 12907.4
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 12712.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 12421.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 12147.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 12140.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 12103.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 12019.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 11962.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 11827.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 11777.8
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 11681.2
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 11572.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 11387.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 11049.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 11025.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 10571.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 10558.2
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 10536.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 10517.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 10342.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 10048.5
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 10046.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 10026.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 9748.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 9676.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 9629.2
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 9600.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 9586.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 9571.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 9483.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 9470.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 9387.1
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 9217.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 8936.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 8823.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 8635.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 8561.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 8551.1
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 8483.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 8425.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 8323.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 8315.2
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 8270.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 8216.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 8090.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 7874.4
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 7795.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 7775.8
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 7715.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 7661.9
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 7654.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 7645.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 7581.6
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 7501.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 7437.9
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 7427.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 7357.6
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 7270.7
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 7243.2
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 7225.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 7192.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 7169.5
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 7130.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 7096.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 7081.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 7063.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 6994.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 6854.2
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 6834.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 6805.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 6774.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 6708.4
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 6553.0
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 6493.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 6402.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 6346.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 6329.3
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 6310.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 6272.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 6266.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 6248.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 6207.7
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 6156.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 6112.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 6101.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 6101.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 6047.6
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 6044.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 6002.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 5940.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 5902.9
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 5880.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 5772.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 5771.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 5716.5
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 5700.9
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 5688.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 5623.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 5599.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 5580.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 5565.3
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 5512.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 5449.3
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 5444.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 5440.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 5268.3
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 5180.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 5170.4
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 5090.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 4981.4
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 4975.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 4957.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 4875.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 4856.8
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 4800.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 4711.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 4676.8
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 4554.6
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 4553.8
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 4481.0
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 4461.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 4409.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 4345.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 4300.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 4282.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 4066.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 3999.5
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 3971.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 3912.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 3890.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 3881.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 3738.6
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 3716.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 3632.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 3576.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 3558.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 3496.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 3334.6
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 3283.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 3265.5
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 3110.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 2964.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2836.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2684.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 2676.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 2656.2
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 2604.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 2560.0
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 2541.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 2532.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 2480.4
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 2461.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 2409.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 2167.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1798.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1788.7
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 1783.9
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 1353.5
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 1079.4
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 1018.9
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 572.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

5108.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 5108.1
FF:10158-103A5 76 years, female 5108.1

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2175.4
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 1647.1
Samples: 1

Max nTPM: 1647.1
Min nTPM: 1647.1
Sample A 1647.1
Midbrain
nTPM: 2175.4
Samples: 1

Max nTPM: 2175.4
Min nTPM: 2175.4
Sample A 2175.4
Superior colliculi
nTPM: 1328.5
Samples: 1

Max nTPM: 1328.5
Min nTPM: 1328.5
Sample A 1328.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6303.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 6042.4
Samples: 3

Max nTPM: 6405.6
Min nTPM: 5679.8
Sample A Female 6405.6
Sample B Female 5679.8
Sample C Male 6041.8
Midbrain
nTPM: 3771.6
Samples: 3

Max nTPM: 5135.2
Min nTPM: 2341.7
Sample B Female 5135.2
Sample C Male 3838.0
Sample D Male 2341.7
Periaqueductal gray
nTPM: 6303.5
Samples: 3

Max nTPM: 7756.3
Min nTPM: 5567.2
Sample B Female 5567.2
Sample C Male 7756.3
Sample D Male 5587.1
Superior colliculi
nTPM: 3484.3
Samples: 4

Max nTPM: 4196.0
Min nTPM: 2041.7
Sample A Female 3557.4
Sample B Female 2041.7
Sample C Male 4142.0
Sample D Male 4196.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

298.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 298.4
Samples: 4

Max nTPM: 310.4
Min nTPM: 275.8
Sample A 302.2
Sample B 310.4
Sample C 275.8
Sample D 305.4

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

292.6
Rat sample Sample description nTPM
Midbrain
nTPM: 292.6
Samples: 4

Max nTPM: 322.4
Min nTPM: 271.1
Sample A 295.7
Sample A 271.1
Sample A 281.3
Sample A 322.4

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