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BETA
  • SUMMARY

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  • BRAIN

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  • PMP2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
Brain proteome
Midbrain
Methods
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:289.6 nTPM
HPA Brain:346.9 nTPM
GTEx:289.6 nTPM
FANTOM5:674.7 Scaled Tags Per Million
Macaque:39.3 nTPM
Mouse:0.0 nTPM
Rat:0.7 nTPM
Pig:185.2 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 10
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 260
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

346.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 223.0
1870 Female, age 42, unknown 279.4
2828 Female, age 72, unknown 266.2
2586 Male, age 75, left hemisphere 246.1
2666 Male, age 74, left hemisphere 232.8
1833 Male, age 53, unknown 225.6
2019 Male, age 18, unknown 218.7
2411 Female, age 72, unknown 209.2
1830 Male, age 51, unknown 206.9
1827 Male, age 72, unknown 200.0
2219 Male, age 76, both hemispheres 145.4
Dorsal raphe nucleus
nTPM: 303.7
2016 Female, age 72, unknown 404.8
1828 Male, age 53, unknown 340.3
2047 Male, age 72, unknown 284.3
2298 Female, age 72, unknown 272.8
2750 Male, age 76, both hemispheres 216.4
Inferior colliculus
nTPM: 330.9
1848 Female, age 42, unknown 377.3
2849 Male, age 72, unknown 347.2
2097 Female, age 72, unknown 339.2
1890 Male, age 53, unknown 259.9
Median raphe nucleus
nTPM: 201.2
2220 Male, age 76, midline 201.2
Periaquaductal grey, anterior
nTPM: 220.4
2502 Female, age 75, unknown 249.1
1795 Male, age 51, unknown 211.3
1947 Male, age 18, unknown 201.0
Periaquaductal grey, dorsal
nTPM: 346.9
2850 Male, age 76, both hemispheres 402.5
1840 Male, age 53, unknown 394.4
2464 Female, age 72, unknown 316.9
1831 Male, age 72, unknown 273.6
Periaquaductal grey, lateral
nTPM: 268.8
2140 Male, age 76, both hemispheres 337.1
2053 Male, age 18, unknown 287.9
2272 Male, age 74, both hemispheres 181.3
Pretectal area
nTPM: 218.0
2224 Female, age 72, unknown 280.8
1817 Female, age 42, unknown 261.7
2825 Male, age 18, unknown 232.0
2316 Male, age 76, right hemisphere 227.7
2407 Male, age 75, both hemispheres 223.6
1815 Male, age 53, unknown 222.2
1944 Female, age 72, unknown 210.8
2273 Male, age 74, both hemispheres 205.7
2667 Female, age 75, unknown 191.0
1816 Male, age 51, unknown 185.4
2007 Male, age 72, unknown 157.3
Red nucleus
nTPM: 289.2
1954 Female, age 42, unknown 404.3
2227 Male, age 72, unknown 350.9
2769 Male, age 72, unknown 344.4
2503 Female, age 72, unknown 326.9
1865 Male, age 51, unknown 325.3
1821 Female, age 72, unknown 317.2
1904 Male, age 53, unknown 295.8
2823 Male, age 76, right hemisphere 279.2
2725 Female, age 75, unknown 236.6
2588 Male, age 74, left hemisphere 213.4
2785 Male, age 18, unknown 208.8
2584 Male, age 75, left hemisphere 167.6
Substantia nigra
nTPM: 220.4
2699 Male, age 18, unknown 367.1
1889 Female, age 72, unknown 253.7
2241 Male, age 72, unknown 213.2
1941 Male, age 53, unknown 209.8
1916 Female, age 42, unknown 200.9
2583 Male, age 75, right hemisphere 199.1
1851 Male, age 51, unknown 196.7
2409 Female, age 72, unknown 194.7
2590 Female, age 75, unknown 191.0
2665 Male, age 74, both hemispheres 177.9
Superior colliculus
nTPM: 231.5
2668 Female, age 75, unknown 301.7
2664 Male, age 75, both hemispheres 296.7
1995 Male, age 72, unknown 278.1
2587 Male, age 74, left hemisphere 243.4
1839 Male, age 51, unknown 237.4
1913 Female, age 42, unknown 227.2
2087 Female, age 72, unknown 216.2
1796 Male, age 53, unknown 181.7
1895 Male, age 76, right hemisphere 167.4
2261 Male, age 18, unknown 164.8
Ventral tegmental area
nTPM: 255.1
2223 Female, age 72, unknown 315.6
1942 Male, age 51, unknown 290.8
2021 Male, age 53, unknown 275.8
1915 Female, age 42, unknown 251.7
2410 Female, age 72, unknown 208.2
2218 Male, age 76, both hemispheres 188.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

289.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 289.6
Samples: 183

Max nTPM: 861.8
Min nTPM: 40.9
Std nTPM: 136.1
Median nTPM: 265.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 861.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 691.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 678.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 675.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 607.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 594.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 575.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 568.3
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 556.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 541.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 541.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 529.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 523.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 512.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 509.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 509.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 507.6
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 498.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 479.8
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 467.4
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 465.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 459.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 456.1
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 445.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 438.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 436.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 434.5
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 430.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 427.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 420.2
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 418.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 414.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 413.3
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 401.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 391.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 388.8
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 382.6
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 378.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 375.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 374.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 371.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 369.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 368.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 359.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 355.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 355.1
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 354.1
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 345.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 344.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 341.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 341.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 340.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 338.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 336.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 335.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 331.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 327.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 326.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 324.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 322.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 321.2
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 319.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 319.2
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 318.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 318.2
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 314.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 314.5
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 312.6
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 309.3
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 306.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 303.1
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 302.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 302.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 301.4
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 299.5
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 297.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 294.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 293.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 291.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 289.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 284.9
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 284.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 283.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 281.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 280.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 279.9
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 279.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 276.8
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 271.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 269.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 266.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 265.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 262.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 262.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 261.3
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 260.7
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 259.8
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 255.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 253.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 248.6
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 247.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 241.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 238.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 237.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 237.1
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 233.9
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 233.3
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 232.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 231.2
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 228.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 228.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 227.4
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 224.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 224.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 222.4
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 222.1
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 221.6
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 221.4
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 219.5
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 219.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 219.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 218.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 217.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 216.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 216.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 216.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 215.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 214.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 213.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 209.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 202.5
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 200.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 199.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 198.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 197.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 195.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 193.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 191.3
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 190.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 188.7
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 186.1
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 186.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 181.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 179.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 175.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 175.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 175.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 174.2
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 168.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 167.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 166.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 166.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 166.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 164.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 164.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 163.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 162.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 159.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 159.8
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 152.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 149.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 149.5
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 149.4
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 149.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 146.0
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 145.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 143.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 142.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 141.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 136.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 128.7
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 126.8
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 114.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 114.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 112.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 112.0
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 111.0
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 95.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 84.8
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 83.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 76.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 53.9
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 40.9
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

674.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 674.7
FF:10158-103A5 76 years, female 674.7

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

39.3
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 39.3
Samples: 1

Max nTPM: 39.3
Min nTPM: 39.3
Sample A 39.3
Midbrain
nTPM: 35.1
Samples: 1

Max nTPM: 35.1
Min nTPM: 35.1
Sample A 35.1
Superior colliculi
nTPM: 23.5
Samples: 1

Max nTPM: 23.5
Min nTPM: 23.5
Sample A 23.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

185.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 185.2
Samples: 3

Max nTPM: 234.4
Min nTPM: 120.2
Sample A Female 200.9
Sample B Female 234.4
Sample C Male 120.2
Midbrain
nTPM: 2.9
Samples: 3

Max nTPM: 7.2
Min nTPM: 0.4
Sample B Female 7.2
Sample C Male 1.0
Sample D Male 0.4
Periaqueductal gray
nTPM: 10.5
Samples: 3

Max nTPM: 19.4
Min nTPM: 3.9
Sample B Female 8.1
Sample C Male 3.9
Sample D Male 19.4
Superior colliculi
nTPM: 12.8
Samples: 4

Max nTPM: 38.4
Min nTPM: 1.2
Sample A Female 38.4
Sample B Female 10.5
Sample C Male 1.2
Sample D Male 1.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A 0.0
Sample B 0.0
Sample C 0.0
Sample D 0.0

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.7
Rat sample Sample description nTPM
Midbrain
nTPM: 0.7
Samples: 4

Max nTPM: 1.0
Min nTPM: 0.5
Sample A 0.5
Sample A 1.0
Sample A 0.6
Sample A 0.6

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