BETA
CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Not detected
Glial cells: Not detected
Neuronal cells: Medium
Neuropil: Not detected
RNA expressioni
Consensus:832.1 nTPM
HPA:570.4 nTPM
HPA Brain:488.4 nTPM
HPA PFC Brain:776.7 nTPM
GTEx:832.1 nTPM
FANTOM5:3.7 Scaled Tags Per Million
Mouse:261.7 nTPM
Rat:14.6 nTPM
Pig:380.3 nTPM
CEREBRAL CORTEX - SINGLE NUCLEI RNA EXPRESSIONi

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NEURONSi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 80
c-1 Excitatory (VGLUT1) CUX2+
c-2 Inhibitory (GAD1/2) LHX6+ T...
c-3 Inhibitory (GAD1/2) CXCL14+...
c-4 Inhibitory (GAD1/2) LHX6+ T...
c-5 Inhibitory (GAD1/2) CXCL14+
c-6 Excitatory (VGLUT1) FOXP2+
c-7 Excitatory (VGLUT1) CUX2+
c-8 Excitatory (VGLUT1)
c-9 Inhibitory (GAD1/2) LHX6+ T...
c-10 Inhibitory (GAD1/2) CXCL14+...
c-11 Inhibitory (GAD1/2) CXCL14+...
c-12 Excitatory (VGLUT1) FOXP2+
c-13 Excitatory (VGLUT1) FOXP2+
c-14 Excitatory (VGLUT1) CUX2+
c-15 Excitatory (VGLUT1) FOXP2+
c-16 Inhibitory (GAD1/2) CXCL14+...
c-17 Excitatory (VGLUT1/2)
c-18 Excitatory (VGLUT1) FOXP2+
c-19 Excitatory (VGLUT1/2) CUX2+
c-20 Inhibitory (GAD1/2) LAMP5+ ...
c-21 Excitatory (VGLUT1) FOXP2+
c-22 Inhibitory (GAD1/2) CXCL14+
c-23 Excitatory (VGLUT1) FOXP2+
c-24 Excitatory (VGLUT1) SOX5+
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NON-NEURONALi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 190
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Oligodendrocyte progenitor ...
c-4 Oligodendrocytes
c-5 Astrocytes
c-6 Astrocytes
c-7 Microglia
c-8 Oligodendrocyte progenitor ...
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Astrocytes
c-12 Astrocytes
c-13 Astrocytes
c-14 Microglia
c-15 Vascular endothelial cells
c-16 Fibroblasts
c-17 Oligodendrocytes (CNTN1+)
c-18 Macrophages
c-19 Immature oligodendrocytes
c-20 Oligodendrocyte progenitor ...
c-21 Pericytes
c-22 Lymphocytes
c-23 Fibroblasts
c-24 Vascular smooth muscle cell
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA058373
Endothelial cells Not detected
Glial cells Not detected
Neuronal cells Medium
Neuropil Not detected



CEREBRAL CORTEX - PROTEINTALKS DB MS
Median intensity 171795
Sample Intensity
Cerebral cortex_01
 190641
Cerebral cortex_02
 171095
Cerebral cortex_03
 209338
Cerebral cortex_04
 174398
Cerebral cortex_05
 100792
Cerebral cortex_06
 165545
Cerebral cortex_07
 189200
Cerebral cortex_08
 162485
Cerebral cortex_09
 142720
Cerebral cortex_10
 216820
Cerebral cortex_11
 141509
Cerebral cortex_12
 186340
Cerebral cortex_13
 191634
Cerebral cortex_14
 170487
Cerebral cortex_15
 219567
Cerebral cortex_16
 137845
Cerebral cortex_17
 156810
Cerebral cortex_18
 172496
Cerebral cortex_19
 218990
Cerebral cortex_20
 190142
Cerebral cortex_21
 118975
Cerebral cortex_22
 166211
Cerebral cortex_23
 152088
Cerebral cortex_24
 188249
Cerebral cortex_25
 179754
Cerebral cortex_26
 192241
Cerebral cortex_27
 167213
Cerebral cortex_28
 82948
Cerebral cortex_29
 97419
Cerebral cortex_30
 149943
Cerebral cortex_31
 201241
Cerebral cortex_32
 111744
Cerebral cortex_33
 272097
Cerebral cortex_34
 175517
Cerebral cortex_35
 295545
Cerebral cortex_36
 140505
Cerebral cortex_37
 182929
Cerebral cortex_38
 157510

CEREBRAL CORTEX - MANN MS
Median intensity 65254458
Replicate Intensity
Cerebral cortex_01
 60899035
Cerebral cortex_02
 65254458
Cerebral cortex_03
 72903663

CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 570.4
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 487.2
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 752.9
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 471.1
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain Stereo-seq

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 488.4
Sample id Sample description nTPM
Angular gyrus
nTPM: 334.2
1866 Male, age 76, both hemispheres 460.5
1790 Male, age 76, right hemisphere 405.5
2103 Male, age 75, left hemisphere 372.5
2260 Female, age 72, left hemisphere 310.9
2221 Female, age 67, right hemisphere 296.2
2602 Female, age 94, right hemisphere 282.2
2265 Female, age 91, left hemisphere 275.5
2722 Male, age 61, left hemisphere 270.3
Angular gyrus (white matter)
nTPM: 455.8
1920 Male, age 76, both hemispheres 455.8
Anterior cingulate cortex, supragenual-dorsal
nTPM: 309.8
1896 Female, age 85, right hemisphere 367.0
2478 Female, age 67, right hemisphere 324.7
2547 Male, age 74, left hemisphere 314.2
2472 Male, age 75, left hemisphere 292.2
2342 Female, age 94, right hemisphere 250.6
Anterior cingulate cortex, supragenual-ventral
nTPM: 310.4
2479 Female, age 67, right hemisphere 370.7
1950 Female, age 85, right hemisphere 323.2
1761 Male, age 74, left hemisphere 316.2
2538 Male, age 75, left hemisphere 279.3
1755 Female, age 94, right hemisphere 262.4
Anterior insular cortex, dorsal
nTPM: 319.9
2235 Female, age 91, right hemisphere 343.9
2670 Male, age 75, left hemisphere 341.5
2001 Male, age 76, right hemisphere 312.6
2506 Female, age 94, right hemisphere 281.6
Anterior insular cortex, ventral
nTPM: 324.0
1925 Female, age 91, left hemisphere 372.4
1852 Male, age 76, left hemisphere 365.7
2596 Male, age 75, left hemisphere 323.4
2262 Female, age 67, right hemisphere 301.7
2507 Female, age 94, left hemisphere 297.7
2757 Male, age 61, right hemisphere 283.2
Area parastriata, inferior
nTPM: 353.2
2509 Female, age 94, left hemisphere 475.0
2234 Male, age 75, left hemisphere 455.6
1789 Male, age 76, right hemisphere 388.2
1758 Female, age 72, right hemisphere 334.0
1760 Female, age 67, left hemisphere 277.4
2268 Male, age 61, right hemisphere 273.7
2421 Female, age 91, left hemisphere 268.1
Area parastriata, parietal
nTPM: 338.3
2420 Male, age 75, left hemisphere 381.4
1785 Male, age 76, right hemisphere 376.9
2233 Male, age 61, right hemisphere 329.0
2680 Female, age 94, right hemisphere 308.0
2236 Female, age 91, left hemisphere 296.2
Area parastriata, superior
nTPM: 442.8
2435 Male, age 61, left hemisphere 664.8
2604 Female, age 94, right hemisphere 523.6
2684 Female, age 67, left hemisphere 402.8
2881 Male, age 76, left hemisphere 387.9
1773 Female, age 91, left hemisphere 339.8
2419 Male, age 75, right hemisphere 337.9
Area parastriata, temporal
nTPM: 317.3
1804 Male, age 76, right hemisphere 384.0
2681 Female, age 94, right hemisphere 323.4
2471 Male, age 75, left hemisphere 303.7
2424 Female, age 67, left hemisphere 294.6
2267 Male, age 61, right hemisphere 281.0
Area striata
nTPM: 334.5
1884 Male, age 76, left hemisphere 457.6
1753 Female, age 72, right hemisphere 378.6
2002 Female, age 91, right hemisphere 335.2
2679 Female, age 94, right hemisphere 306.3
2417 Male, age 61, right hemisphere 273.3
2427 Female, age 91, left hemisphere 255.9
Area striata (white matter)
nTPM: 377.9
2258 Female, age 91, left hemisphere 377.9
Claustrum
nTPM: 356.0
2196 Female, age 79, unknown 445.9
2392 Female, age 94, both hemispheres 439.1
2491 Male, age 75, both hemispheres 403.3
2198 Male, age 80, both hemispheres 373.5
2292 Female, age 85, both hemispheres 347.1
1956 Male, age 74, unknown 337.5
2568 Male, age 61, both hemispheres 302.7
2284 Female, age 91, both hemispheres 289.2
2645 Female, age 72, unknown 265.8
Corpus callosum, genu (white matter)
nTPM: 488.4
1885 Female, age 94, left hemisphere 567.9
1934 Male, age 61, right hemisphere 559.8
1887 Male, age 76, left hemisphere 511.3
1849 Female, age 91, right hemisphere 435.4
2771 Male, age 75, left hemisphere 435.1
1886 Female, age 67, right hemisphere 421.2
Corpus callosum, splenium (white matter)
nTPM: 487.4
2238 Female, age 94, right hemisphere 535.4
1946 Male, age 76, left hemisphere 483.0
2847 Female, age 67, right hemisphere 472.4
2104 Male, age 75, left hemisphere 458.9
Frontal eye field
nTPM: 319.2
2147 Male, age 61, left hemisphere 453.7
2543 Male, age 74, left hemisphere 285.4
2761 Female, age 94, left hemisphere 274.5
2441 Male, age 75, left hemisphere 263.0
Frontal operculum
nTPM: 313.1
2348 Male, age 75, left hemisphere 334.9
2030 Male, age 61, right hemisphere 333.8
2781 Female, age 85, right hemisphere 270.5
Fusiform gyrus
nTPM: 373.3
2074 Female, age 91, left hemisphere 477.0
2431 Male, age 75, right hemisphere 462.9
1807 Male, age 76, left hemisphere 405.0
2112 Male, age 80, both hemispheres 349.0
2784 Female, age 85, left hemisphere 312.6
2433 Female, age 72, left hemisphere 308.3
2617 Female, age 94, left hemisphere 298.0
Inferior frontal gyrus, opercular
nTPM: 304.4
2866 Male, age 61, right hemisphere 388.6
2865 Male, age 61, left hemisphere 338.7
2871 Female, age 94, left hemisphere 319.2
2874 Female, age 85, right hemisphere 317.0
2873 Female, age 85, left hemisphere 304.7
2868 Male, age 75, right hemisphere 280.5
2872 Female, age 94, right hemisphere 279.0
2869 Male, age 74, left hemisphere 278.0
2875 Female, age 67, left hemisphere 271.5
2867 Male, age 75, left hemisphere 266.6
Inferior parietal lobule
nTPM: 306.5
2606 Female, age 67, right hemisphere 363.3
2418 Male, age 75, left hemisphere 306.5
2599 Female, age 94, left hemisphere 300.4
2876 Male, age 76, right hemisphere 255.6
Inferior temporal gyrus
nTPM: 347.1
1880 Male, age 80, right hemisphere 380.7
1808 Male, age 76, left hemisphere 377.0
2430 Male, age 75, right hemisphere 355.4
1970 Female, age 85, right hemisphere 335.4
1965 Female, age 91, left hemisphere 322.3
2689 Female, age 94, right hemisphere 311.9
Intraparietal deep sulcus
nTPM: 345.2
2230 Male, age 61, right hemisphere 429.8
2600 Female, age 94, right hemisphere 362.8
2798 Male, age 76, left hemisphere 348.3
2607 Female, age 67, right hemisphere 329.2
2102 Female, age 91, left hemisphere 317.4
2669 Male, age 75, left hemisphere 283.8
Lingual gyrus
nTPM: 348.4
1893 Male, age 76, left hemisphere 389.4
2688 Male, age 75, right hemisphere 360.1
2073 Female, age 85, left hemisphere 353.1
2838 Male, age 80, right hemisphere 326.9
2618 Female, age 94, left hemisphere 312.5
Middle cingulate cortex
nTPM: 296.4
2640 Female, age 94, right hemisphere 356.4
2633 Male, age 74, left hemisphere 303.3
2539 Male, age 75, left hemisphere 284.8
2028 Female, age 85, left hemisphere 274.5
2357 Female, age 67, right hemisphere 263.2
Middle temporal gyrus
nTPM: 318.7
1819 Male, age 80, right hemisphere 384.2
1799 Male, age 76, left hemisphere 351.5
2034 Female, age 91, right hemisphere 298.0
2616 Female, age 94, left hemisphere 297.6
2611 Male, age 75, right hemisphere 262.5
Occipital cortex
nTPM: 297.6
1842 Male, age 76, right hemisphere 368.9
2426 Male, age 75, midline 309.7
2677 Female, age 67, right hemisphere 293.1
2470 Male, age 75, right hemisphere 288.1
2608 Female, age 67, both hemispheres 228.2
Occipital cortex (white matter)
nTPM: 407.7
2259 Male, age 75, midline 481.7
2257 Female, age 67, both hemispheres 333.7
Olfactory area
nTPM: 328.4
1805 Female, age 85, right hemisphere 381.5
2542 Male, age 74, left hemisphere 356.6
2440 Male, age 75, left hemisphere 349.2
2756 Female, age 67, right hemisphere 324.5
2222 Female, age 67, right hemisphere 313.6
2352 Female, age 94, right hemisphere 244.7
Olfactory tubercle
nTPM: 339.8
1846 Male, age 80, right hemisphere 387.7
1998 Female, age 91, both hemispheres 336.4
2487 Female, age 94, left hemisphere 322.7
2856 Male, age 75, right hemisphere 312.6
Orbitofrontal gyrus, anterior
nTPM: 290.5
2863 Female, age 85, right hemisphere 365.3
2864 Female, age 67, left hemisphere 302.8
2862 Female, age 85, left hemisphere 203.4
Paracentral lobule, anterior
nTPM: 306.1
1926 Male, age 61, left hemisphere 353.5
1776 Female, age 85, right hemisphere 343.3
1754 Male, age 75, left hemisphere 332.3
2340 Female, age 67, right hemisphere 307.6
2474 Male, age 74, left hemisphere 251.3
2638 Female, age 94, right hemisphere 248.6
Paracentral lobule, posterior
nTPM: 312.2
2551 Female, age 94, right hemisphere 389.1
1775 Female, age 85, right hemisphere 360.1
2345 Male, age 61, left hemisphere 282.8
2446 Male, age 75, left hemisphere 276.1
1764 Male, age 74, right hemisphere 252.8
Parahippocampal cortex (white matter)
nTPM: 418.4
2157 Female, age 91, both hemispheres 418.4
Parietal operculum
nTPM: 271.6
2356 Female, age 67, right hemisphere 295.8
1763 Male, age 74, left hemisphere 279.5
2719 Male, age 75, left hemisphere 272.4
2552 Female, age 94, right hemisphere 238.7
Parieto-insular cortex
nTPM: 310.3
1976 Female, age 91, right hemisphere 404.6
2831 Male, age 76, right hemisphere 321.5
2232 Male, age 61, right hemisphere 302.3
2508 Female, age 94, right hemisphere 262.0
2671 Male, age 75, left hemisphere 261.0
Parieto-occipital transitional area
nTPM: 330.5
2683 Female, age 67, left hemisphere 381.6
1784 Male, age 76, right hemisphere 376.4
2468 Male, age 75, left hemisphere 314.2
2674 Female, age 94, right hemisphere 303.2
2270 Male, age 61, right hemisphere 276.9
Parieto-temporal junction (white matter)
nTPM: 407.3
1935 Female, age 94, right hemisphere 476.0
2121 Male, age 76, left hemisphere 425.9
1999 Female, age 67, right hemisphere 398.7
2469 Male, age 75, right hemisphere 397.7
2774 Male, age 61, right hemisphere 392.5
2770 Female, age 91, right hemisphere 353.0
Piriform cortex
nTPM: 348.8
2347 Male, age 75, right hemisphere 424.8
2153 Female, age 85, left hemisphere 272.8
Postcentral gyrus
nTPM: 256.7
2533 Male, age 75, right hemisphere 256.7
Postcentral gyrus, dorsal
nTPM: 331.3
1836 Female, age 85, right hemisphere 384.4
2151 Male, age 61, left hemisphere 368.3
2350 Male, age 75, left hemisphere 360.3
2477 Female, age 94, right hemisphere 349.5
2339 Female, age 67, right hemisphere 291.8
2544 Male, age 74, left hemisphere 233.4
Postcentral gyrus, middle
nTPM: 289.9
2248 Male, age 61, left hemisphere 363.5
1897 Female, age 85, right hemisphere 359.3
2146 Female, age 67, right hemisphere 293.4
2444 Male, age 75, left hemisphere 225.1
2545 Male, age 74, left hemisphere 208.0
Postcentral gyrus, ventral
nTPM: 306.2
2836 Female, age 94, right hemisphere 322.5
2024 Female, age 85, right hemisphere 310.0
2445 Male, age 75, left hemisphere 285.9
Posterior cingulate cortex
nTPM: 329.3
2553 Female, age 94, right hemisphere 377.5
2473 Male, age 75, left hemisphere 315.8
1759 Male, age 74, right hemisphere 294.4
Posterior cingulate cortex, dorsal
nTPM: 314.1
2634 Male, age 74, left hemisphere 337.7
2556 Female, age 67, right hemisphere 322.2
2343 Male, age 61, left hemisphere 312.5
2641 Female, age 94, right hemisphere 306.7
2540 Male, age 75, right hemisphere 306.0
2076 Female, age 85, right hemisphere 299.8
Posterior cingulate cortex, ventral
nTPM: 296.1
2541 Male, age 75, right hemisphere 317.4
2448 Female, age 67, right hemisphere 315.9
1994 Female, age 85, right hemisphere 305.6
1762 Female, age 94, right hemisphere 294.9
2635 Male, age 74, left hemisphere 278.6
2346 Male, age 61, left hemisphere 264.0
Posterior insular cortex
nTPM: 298.2
2832 Female, age 91, right hemisphere 348.6
1823 Male, age 76, right hemisphere 330.0
2511 Female, age 67, right hemisphere 325.1
2597 Male, age 75, left hemisphere 274.4
2231 Male, age 61, left hemisphere 255.9
2603 Female, age 94, left hemisphere 255.0
Precentral gyrus
nTPM: 220.8
2557 Male, age 75, right hemisphere 220.8
Precentral gyrus, dorsal
nTPM: 307.1
1756 Male, age 74, left hemisphere 325.6
2442 Male, age 75, left hemisphere 314.6
2476 Female, age 94, right hemisphere 310.2
2354 Female, age 67, right hemisphere 278.0
Precentral gyrus, middle
nTPM: 321.3
2475 Male, age 74, right hemisphere 394.2
1969 Female, age 67, right hemisphere 325.2
1909 Male, age 61, left hemisphere 322.2
2443 Male, age 75, left hemisphere 303.7
2549 Female, age 94, right hemisphere 260.9
Precentral gyrus, ventral
nTPM: 322.2
2662 Female, age 67, right hemisphere 370.9
2678 Male, age 74, left hemisphere 317.7
2550 Female, age 94, right hemisphere 309.8
2630 Male, age 75, left hemisphere 290.5
Precuneus
nTPM: 334.4
1782 Male, age 76, right hemisphere 394.0
2467 Male, age 75, right hemisphere 382.3
2673 Female, age 94, right hemisphere 362.9
2510 Female, age 67, right hemisphere 312.0
1780 Female, age 91, right hemisphere 289.0
2594 Male, age 61, left hemisphere 266.1
Premotor cortex, dorsal
nTPM: 313.3
1878 Female, age 85, right hemisphere 368.4
2554 Female, age 67, right hemisphere 325.6
2027 Male, age 61, left hemisphere 302.9
2536 Male, age 75, left hemisphere 302.9
2631 Male, age 74, left hemisphere 266.7
Premotor cortex, ventral
nTPM: 301.2
1881 Female, age 85, right hemisphere 352.5
1777 Female, age 67, left hemisphere 333.9
1779 Male, age 61, left hemisphere 322.4
2349 Male, age 75, left hemisphere 299.0
1757 Male, age 74, left hemisphere 262.9
2637 Female, age 94, right hemisphere 236.5
Retrosplenial cortex
nTPM: 365.2
1914 Male, age 76, right hemisphere 404.0
1951 Male, age 61, right hemisphere 372.1
2675 Female, age 94, left hemisphere 319.4
Somatomor cortex, precentral gyrus (white matter)
nTPM: 347.2
2439 Male, age 75, right hemisphere 347.2
Somatosensory cortex, postcentral gyrus, ventral (white matter)
nTPM: 319.5
2623 Male, age 75, right hemisphere 319.5
Subcentral gyrus, S2
nTPM: 317.5
2555 Female, age 67, right hemisphere 364.8
2072 Male, age 61, left hemisphere 352.2
2762 Male, age 74, left hemisphere 330.7
2351 Male, age 75, left hemisphere 298.0
1964 Female, age 85, right hemisphere 289.1
2839 Female, age 94, right hemisphere 270.1
Superior parietal lobule
nTPM: 331.4
1800 Male, age 76, right hemisphere 413.1
1992 Female, age 91, right hemisphere 347.7
2605 Female, age 67, right hemisphere 311.7
2229 Male, age 61, right hemisphere 295.2
2672 Female, age 94, right hemisphere 289.1
Superior temporal gyrus
nTPM: 326.5
1844 Female, age 91, left hemisphere 384.2
2025 Male, age 80, right hemisphere 345.1
1843 Male, age 76, left hemisphere 344.3
2615 Female, age 94, left hemisphere 300.4
2687 Male, age 75, right hemisphere 258.4
Supplementary motor cortex
nTPM: 283.4
1993 Male, age 61, left hemisphere 379.6
2537 Male, age 75, left hemisphere 257.8
2548 Female, age 94, right hemisphere 253.8
2632 Male, age 74, left hemisphere 242.6
Supramarginal gyrus
nTPM: 331.9
1798 Male, age 76, right hemisphere 378.3
1991 Female, age 91, right hemisphere 340.2
2601 Female, age 94, left hemisphere 333.1
2513 Female, age 72, left hemisphere 327.3
2415 Male, age 61, left hemisphere 280.7
Temporal pole
nTPM: 400.8
2518 Male, age 75, right hemisphere 441.5
1853 Female, age 85, right hemisphere 435.9
1832 Female, age 91, left hemisphere 418.0
1826 Male, age 76, right hemisphere 354.5
2612 Female, age 94, left hemisphere 354.4
Temporal white matter
nTPM: 479.0
2523 Female, age 94, left hemisphere 820.5
2736 Female, age 91, right hemisphere 422.6
1801 Male, age 76, left hemisphere 417.9
2254 Male, age 75, right hemisphere 390.1
2524 Female, age 85, left hemisphere 343.9
Temporo-insular cortex, parainsular gyrus
nTPM: 284.6
2598 Male, age 75, left hemisphere 349.2
1802 Male, age 76, left hemisphere 326.6
2512 Female, age 67, right hemisphere 298.6
2264 Female, age 91, right hemisphere 270.1
2416 Male, age 61, right hemisphere 256.1
2676 Female, age 94, right hemisphere 206.8
Temporo-occipital transitional zone
nTPM: 389.7
1900 Male, age 76, left hemisphere 450.2
1793 Male, age 80, right hemisphere 399.3
2251 Female, age 85, right hemisphere 319.5
Transversal temporal gyrus, anterior
nTPM: 328.9
1888 Female, age 91, left hemisphere 364.1
1910 Male, age 80, right hemisphere 353.8
2522 Female, age 94, left hemisphere 336.3
1809 Male, age 76, right hemisphere 317.1
2610 Male, age 75, right hemisphere 273.1
Transversal temporal gyrus, posterior
nTPM: 321.5
2833 Male, age 80, right hemisphere 348.2
1922 Male, age 76, left hemisphere 334.4
1967 Female, age 91, right hemisphere 333.0
2520 Male, age 75, right hemisphere 307.9
2614 Female, age 94, left hemisphere 284.0

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 776.7
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 500.2
1514 Male, age 74, right hemisphere 694.6
1517 Female, age 67, left hemisphere 626.5
1513 Male, age 74, left hemisphere 570.9
1512 Male, age 75, left hemisphere 564.2
1518 Female, age 67, right hemisphere 538.6
1515 Female, age 94, right hemisphere 506.9
1510 Male, age 61, left hemisphere 386.5
1511 Male, age 61, right hemisphere 333.7
1516 Female, age 85, left hemisphere 279.9
Anterior cingulate gyrus, pregenual-ventral
nTPM: 563.6
1522 Male, age 74, right hemisphere 698.9
1521 Male, age 74, left hemisphere 645.4
1523 Female, age 67, left hemisphere 567.2
1520 Male, age 75, right hemisphere 534.6
1519 Male, age 61, left hemisphere 371.7
Anterior cingulate gyrus, subgenual
nTPM: 492.7
1527 Male, age 74, left hemisphere 683.1
1526 Male, age 75, right hemisphere 549.7
1528 Male, age 74, right hemisphere 542.1
1530 Female, age 67, right hemisphere 538.7
1525 Male, age 75, left hemisphere 474.0
1524 Male, age 61, left hemisphere 342.6
1529 Female, age 85, left hemisphere 318.8
Dorsolateral prefrontal cortex
nTPM: 690.1
1450 Female, age 67, right hemisphere 901.7
1446 Male, age 74, right hemisphere 734.1
1447 Female, age 94, left hemisphere 727.9
1448 Female, age 94, right hemisphere 677.0
1444 Male, age 75, left hemisphere 663.8
1445 Male, age 75, right hemisphere 614.4
1449 Female, age 85, right hemisphere 511.7
Dorsomedial prefrontal cortex
nTPM: 776.7
1442 Male, age 75, right hemisphere 956.7
1443 Female, age 67, right hemisphere 929.7
1441 Male, age 75, left hemisphere 789.7
1439 Male, age 61, left hemisphere 739.4
1440 Male, age 61, right hemisphere 467.8
Frontomarginal cortex
nTPM: 737.9
1471 Female, age 85, left hemisphere 979.8
1468 Male, age 74, left hemisphere 885.0
1472 Female, age 67, left hemisphere 844.6
1470 Female, age 94, right hemisphere 824.4
1467 Male, age 75, right hemisphere 735.5
1469 Female, age 94, left hemisphere 673.5
1473 Female, age 67, right hemisphere 656.9
1466 Male, age 61, right hemisphere 592.0
1465 Male, age 61, left hemisphere 448.9
Frontopolar cortex
nTPM: 643.1
1461 Male, age 75, right hemisphere 983.1
1464 Female, age 67, right hemisphere 690.8
1463 Female, age 67, left hemisphere 689.9
1460 Male, age 75, left hemisphere 628.6
1462 Female, age 94, left hemisphere 544.6
1459 Male, age 61, right hemisphere 540.3
1458 Male, age 61, left hemisphere 424.3
Gyrus rectus
nTPM: 685.9
1478 Female, age 94, left hemisphere 955.3
1477 Male, age 75, right hemisphere 850.8
1481 Female, age 67, left hemisphere 672.7
1479 Female, age 94, right hemisphere 672.0
1480 Female, age 85, left hemisphere 660.4
1476 Male, age 75, left hemisphere 623.2
1475 Male, age 61, right hemisphere 552.1
1474 Male, age 61, left hemisphere 500.4
Inferior frontal gyrus, orbital
nTPM: 590.3
1507 Female, age 85, left hemisphere 949.1
1509 Female, age 67, right hemisphere 810.8
1505 Male, age 74, right hemisphere 699.7
1504 Male, age 74, left hemisphere 602.8
1506 Female, age 94, left hemisphere 584.4
1501 Male, age 61, right hemisphere 558.9
1503 Male, age 75, right hemisphere 480.6
1502 Male, age 75, left hemisphere 450.7
1508 Female, age 85, right hemisphere 396.4
1500 Male, age 61, left hemisphere 369.4
Inferior frontal gyrus, triangular
nTPM: 457.9
1545 Male, age 74, right hemisphere 577.7
1544 Male, age 75, right hemisphere 563.4
1546 Female, age 94, right hemisphere 560.8
1549 Female, age 67, left hemisphere 518.0
1547 Female, age 85, left hemisphere 378.0
1542 Male, age 61, left hemisphere 364.1
1543 Male, age 61, right hemisphere 352.1
1548 Female, age 85, right hemisphere 349.4
Orbitofrontal gyrus, lateral
nTPM: 475.8
1499 Female, age 67, right hemisphere 584.5
1497 Female, age 85, left hemisphere 546.1
1495 Female, age 94, left hemisphere 483.9
1496 Female, age 94, right hemisphere 463.5
1498 Female, age 85, right hemisphere 435.1
1493 Male, age 61, right hemisphere 427.4
1494 Male, age 75, left hemisphere 389.9
Orbitofrontal gyrus, medial
nTPM: 699.4
1485 Male, age 74, left hemisphere 1287.7
1486 Male, age 74, right hemisphere 810.4
1484 Male, age 75, right hemisphere 778.1
1492 Female, age 67, right hemisphere 759.4
1487 Female, age 94, left hemisphere 739.1
1482 Male, age 61, left hemisphere 649.5
1483 Male, age 75, left hemisphere 640.4
1491 Female, age 67, left hemisphere 609.2
1488 Female, age 94, right hemisphere 598.8
1490 Female, age 85, right hemisphere 432.2
1489 Female, age 85, left hemisphere 389.1
Orbitofrontal gyrus, posterior
nTPM: 557.5
1540 Female, age 67, left hemisphere 1115.7
1541 Female, age 67, right hemisphere 928.6
1535 Male, age 74, left hemisphere 707.4
1534 Male, age 75, right hemisphere 562.7
1536 Female, age 94, left hemisphere 515.7
1533 Male, age 75, left hemisphere 484.6
1537 Female, age 94, right hemisphere 418.5
1539 Female, age 85, right hemisphere 376.2
1531 Male, age 61, left hemisphere 375.6
1532 Male, age 61, right hemisphere 327.4
1538 Female, age 85, left hemisphere 320.4
Subcallosal gyrus
nTPM: 679.4
1550 Male, age 61, left hemisphere 1369.1
1561 Female, age 67, right hemisphere 878.0
1552 Male, age 75, left hemisphere 785.2
1560 Female, age 67, left hemisphere 726.7
1553 Male, age 75, right hemisphere 724.0
1554 Male, age 74, left hemisphere 616.0
1557 Female, age 94, right hemisphere 599.0
1556 Female, age 94, left hemisphere 577.0
1555 Male, age 74, right hemisphere 543.0
1559 Female, age 85, right hemisphere 482.8
1558 Female, age 85, left hemisphere 437.8
1551 Male, age 61, right hemisphere 413.9
Superior frontal gyrus
nTPM: 599.0
1566 Male, age 74, right hemisphere 884.0
1571 Female, age 67, right hemisphere 863.6
1567 Female, age 94, left hemisphere 680.0
1565 Male, age 75, right hemisphere 644.1
1564 Male, age 75, left hemisphere 598.7
1568 Female, age 94, right hemisphere 548.1
1562 Male, age 61, left hemisphere 491.7
1569 Female, age 85, left hemisphere 451.6
1570 Female, age 85, right hemisphere 436.8
1563 Male, age 61, right hemisphere 391.3
Temporal cortex
nTPM: 585.4
1591 Male, age 75, right hemisphere 1058.9
1592 Male, age 74, left hemisphere 705.8
1593 Male, age 74, right hemisphere 551.1
1594 Female, age 94, left hemisphere 497.9
1590 Male, age 61, right hemisphere 452.2
1595 Female, age 94, right hemisphere 449.7
1596 Female, age 85, right hemisphere 382.5
Ventrolateral prefrontal cortex
nTPM: 689.2
1456 Female, age 67, left hemisphere 828.0
1457 Female, age 67, right hemisphere 795.8
1453 Male, age 74, right hemisphere 746.9
1454 Female, age 94, left hemisphere 679.7
1451 Male, age 75, right hemisphere 653.6
1452 Male, age 74, left hemisphere 618.5
1455 Female, age 85, right hemisphere 502.0
Ventromedial prefrontal cortex
nTPM: 739.8
1438 Female, age 67, left hemisphere 874.8
1436 Female, age 85, left hemisphere 864.1
1432 Male, age 61, left hemisphere 805.4
1435 Female, age 94, right hemisphere 794.7
1434 Male, age 75, right hemisphere 701.9
1433 Male, age 61, right hemisphere 629.6
1437 Female, age 85, right hemisphere 508.3

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 832.1
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 832.1
Samples: 233

Max nTPM: 1933.2
Min nTPM: 425.4
Std nTPM: 230.5
Median nTPM: 795.0
GTEX-14JG1-0011-R3a-SM-62LEC 40-49 years, male 1933.2
GTEX-1MJK2-0011-R3a-SM-F2TBD 50-59 years, male 1625.6
GTEX-1JMQJ-0011-R3b-SM-EY5ZJ 50-59 years, male 1619.9
GTEX-14E7W-0011-R3b-SM-5YYB5 70-79 years, male 1536.8
GTEX-16YQH-0011-R3a-SM-7EPGM 30-39 years, male 1510.1
GTEX-1EH9U-0011-R3b-SM-CL534 60-69 years, male 1501.7
GTEX-1JMPZ-0011-R3a-SM-EYYWX 30-39 years, male 1375.1
GTEX-1F7RK-0011-R3b-SM-9OSWJ 20-29 years, female 1334.8
GTEX-139T8-0011-R3b-SM-5HL4R 60-69 years, male 1330.7
GTEX-1KWVE-0011-R3b-SM-F649X 30-39 years, male 1327.8
GTEX-1QMI2-0011-R3b-SM-F2TA4 60-69 years, male 1298.2
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Brain - Cortex
Average nTPM: 699.1
Samples: 270

Max nTPM: 1272.7
Min nTPM: 427.3
Std nTPM: 137.5
Median nTPM: 672.2
GTEX-11NV4-2126-SM-5N9DS 60-69 years, male 1272.7
GTEX-1HFI6-3026-SM-CNPPJ 40-49 years, male 1183.9
GTEX-OHPN-2526-SM-2I5H3 60-69 years, female 1155.5
GTEX-15UF6-3026-SM-7KUKL 70-79 years, female 1127.5
GTEX-1HB9E-2926-SM-D4P3S 50-59 years, male 1086.2
GTEX-147GR-3026-SM-5S2ML 60-69 years, male 1049.3
GTEX-13JUV-2926-SM-5LZX7 40-49 years, female 1020.8
GTEX-15RJE-3026-SM-7KUM1 40-49 years, male 1019.6
GTEX-17EVP-3026-SM-7IGQL 40-49 years, male 1003.8
GTEX-1LKK1-3126-SM-EWRNY 50-59 years, female 996.7
GTEX-1F7RK-1826-SM-7RHI4 20-29 years, female 982.8
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Brain - Frontal Cortex (BA9)
Average nTPM: 738.5
Samples: 269

Max nTPM: 1730.8
Min nTPM: 448.1
Std nTPM: 207.7
Median nTPM: 691.0
GTEX-ZAK1-0011-R10a-SM-H7OGG 50-59 years, female 1730.8
GTEX-1RAZS-0011-R10a-SM-F649Y 50-59 years, male 1666.5
GTEX-1IL2V-0011-R10a-SM-CL55A 70-79 years, male 1588.3
GTEX-1N2DW-0011-R10a-SM-F341J 50-59 years, male 1442.9
GTEX-ZE7O-0011-R10a-SM-57WAZ 50-59 years, female 1415.6
GTEX-1O9I2-0011-R10b-SM-F2I33 50-59 years, male 1401.5
GTEX-11ZU8-0011-R10a-SM-GI4W8 60-69 years, male 1309.8
GTEX-15UF6-0011-R10b-SM-9OSVF 70-79 years, female 1295.4
GTEX-11TTK-0011-R10b-SM-DO925 60-69 years, female 1263.9
GTEX-1QMI2-0011-R10a-SM-F3428 60-69 years, male 1263.2
GTEX-1LVAO-0011-R10b-SM-F2TB6 60-69 years, male 1188.1
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 3.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 2.5
FF:10163-103B1 76 years, female 2.5
Postcentral gyrus
Scaled Tags Per Million: 2.4
FF:10032-101E5 44-52 years, mixed 2.4
Frontal lobe
Scaled Tags Per Million: 2.3
FF:10040-101F4 32-61 years, mixed 2.3
Insula
Scaled Tags Per Million: 1.8
FF:10039-101F3 20-68 years, mixed 1.8
Medial frontal gyrus
Scaled Tags Per Million: 3.0
FF:10150-102I6 76 years, female 3.0
Medial temporal gyrus
Scaled Tags Per Million: 3.7
FF:10156-103A3 76 years, female 4.2
FF:10183-103D3 60 years, female 3.1
Occipital lobe
Scaled Tags Per Million: 2.0
FF:10076-102A4 27 years, male 2.0
Occipital pole
Scaled Tags Per Million: 1.1
FF:10036-101E9 22-68 years, mixed 1.1
Paracentral gyrus
Scaled Tags Per Million: 2.6
FF:10035-101E8 22-69 years, mixed 2.6
Parietal lobe
Scaled Tags Per Million: 2.0
FF:10157-103A4 76 years, female 2.3
FF:10171-103B9 60 years, female 2.0
FF:10034-101E7 35-89 years, mixed 1.7
Temporal lobe
Scaled Tags Per Million: 1.5
FF:10031-101E4 32-61 years, mixed 1.5

CEREBRAL CORTEX - Pig RNA-seqi
Max subtype nTPMi 380.3
Pig sample Sample description nTPM
Occipital cortex
nTPM: 357.2
Samples: 4

Max nTPM: 407.4
Min nTPM: 336.7
Sample A Female 336.7
Sample B Female 337.8
Sample C Male 407.4
Sample D Male 347.0
Retrosplenial cortex
nTPM: 334.9
Samples: 4

Max nTPM: 389.1
Min nTPM: 280.2
Sample A Female 389.1
Sample B Female 362.6
Sample C Male 307.6
Sample D Male 280.2
Cingulate cortex
nTPM: 325.9
Samples: 4

Max nTPM: 375.3
Min nTPM: 276.6
Sample A Female 375.3
Sample B Female 276.6
Sample C Male 368.1
Sample D Male 283.5
Insular cortex
nTPM: 316.8
Samples: 4

Max nTPM: 400.4
Min nTPM: 234.4
Sample A Female 400.4
Sample B Female 318.2
Sample C Male 314.3
Sample D Male 234.4
Motor cortex
nTPM: 380.3
Samples: 4

Max nTPM: 487.0
Min nTPM: 311.0
Sample A Female 400.4
Sample B Female 322.8
Sample C Male 487.0
Sample D Male 311.0
Prefrontal cortex
nTPM: 316.7
Samples: 4

Max nTPM: 343.8
Min nTPM: 287.0
Sample A Female 343.8
Sample B Female 302.6
Sample C Male 333.4
Sample D Male 287.0
Somatosensory cortex
nTPM: 361.4
Samples: 3

Max nTPM: 386.9
Min nTPM: 333.6
Sample B Female 386.9
Sample C Male 363.6
Sample D Male 333.6
Temporal cortex
nTPM: 329.1
Samples: 3

Max nTPM: 426.9
Min nTPM: 236.3
Sample A Female 426.9
Sample B Female 236.3
Sample D Male 324.2

CEREBRAL CORTEX - Mouse RNA-seqi
Max subtype nTPMi 261.7
Mouse sample Sample description nTPM
Motor and prefrontal cortex
nTPM: 237.2
Samples: 4

Max nTPM: 254.8
Min nTPM: 197.0
Sample A 254.8
Sample B 251.9
Sample C 245.0
Sample D 197.0
Retrosplenial and cingulate cortex
nTPM: 245.0
Samples: 3

Max nTPM: 260.5
Min nTPM: 231.3
Sample A 260.5
Sample B 243.2
Sample C 231.3
Somatosensory cortex
nTPM: 261.7
Samples: 4

Max nTPM: 274.3
Min nTPM: 242.8
Sample A 242.8
Sample B 269.6
Sample C 260.1
Sample D 274.3
Visual cortex
nTPM: 244.4
Samples: 4

Max nTPM: 265.3
Min nTPM: 219.7
Sample A 251.4
Sample B 219.7
Sample C 241.3
Sample D 265.3

CEREBRAL CORTEX - Rat RNA-seq
Max subtype nTPMi 14.6
Rat sample Sample description nTPM
Occipital cortex
nTPM: 14.6
Samples: 4

Max nTPM: 16.7
Min nTPM: 12.6
Sample A 12.6
Sample A 13.8
Sample A 16.7
Sample A 15.5
Retrosplenial and cingulate cortex
nTPM: 12.4
Samples: 4

Max nTPM: 12.9
Min nTPM: 11.7
Sample A 12.5
Sample A 12.9
Sample B 12.6
Sample A 11.7
Somatosensory cortex
nTPM: 12.8
Samples: 4

Max nTPM: 13.3
Min nTPM: 12.1
Sample A 13.1
Sample A 13.3
Sample A 12.1
Sample A 12.7

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