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HPA
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TISSUE PRIMARY DATA TISSUES Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
ANTIBODY PRIMARY DATAi

The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.

The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.

For histological reference, visit the histological dictionary.

Antibodies in assayi

The internal antibody ID for the antibody/antibodies available for this specific target, click link for more antibody information.

HPA001032 , HPA027214 , CAB037024
Tissue presentation order  
Organ
Cell type
Alphabetical
Tissue Antibody stainingi

This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.

Annotated protein expressioni

This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.

HPA001032

HPA027214

CAB037024

h
m
l
n
h
m
l
n
h
m
l
n
h
m
l
n
Brain
Cerebral cortex Neuronal cells
Cerebral cortex Endothelial cells
Cerebral cortex Glial cells
Cerebral cortex Neuropil
Hippocampus Neuronal cells
Hippocampus Glial cells
Caudate Neuronal cells
Caudate Glial cells
Cerebellum Purkinje cells
Cerebellum Cells in granular layer
Cerebellum Cells in molecular layer
Endocrine tissues
Thyroid gland Glandular cells
Parathyroid gland Glandular cells
Adrenal gland Glandular cells
Respiratory system
Nasopharynx Respiratory epithelial cells
Bronchus Respiratory epithelial cells
Lung Alveolar cells
N/A
Lung Macrophages
Lung Alveolar cells type I
N/A
N/A
Lung Alveolar cells type II
N/A
N/A
Lung Endothelial cells
N/A
N/A
Proximal digestive tract
Oral mucosa Squamous epithelial cells
Salivary gland Glandular cells
Esophagus Squamous epithelial cells
Gastrointestinal tract
Stomach 1 Glandular cells
Stomach 2 Glandular cells
Duodenum Glandular cells
Small intestine Glandular cells
Colon Endothelial cells
Colon Glandular cells
Colon Peripheral nerve/ganglion
N/A
Rectum Glandular cells
Liver & Gallbladder
Liver Hepatocytes
Liver Cholangiocytes
Gallbladder Glandular cells
Pancreas
Pancreas Exocrine glandular cells
Pancreas Pancreatic endocrine cells
Kidney & Urinary bladder
Kidney Cells in glomeruli
Kidney Cells in tubules
N/A
Kidney Bowman's capsule
N/A
N/A
Kidney Collecting ducts
N/A
N/A
Kidney Distal tubules
N/A
N/A
Kidney Proximal tubules (cell body)
N/A
N/A
Kidney Proximal tubules (microvilli)
N/A
N/A
Urinary bladder Urothelial cells
N/A
Male reproductive system
Testis Cells in seminiferous ducts
N/A
Testis Elongated or late spermatids
N/A
N/A
Testis Leydig cells
Testis Pachytene spermatocytes
N/A
N/A
Testis Peritubular cells
N/A
N/A
Testis Preleptotene spermatocytes
N/A
N/A
Testis Round or early spermatids
N/A
N/A
Testis Sertoli cells
N/A
N/A
Testis Spermatogonia cells
N/A
N/A
Epididymis Glandular cells
Prostate Glandular cells
Seminal vesicle Glandular cells
Breast and female reproductive system
Breast Adipocytes
Breast Glandular cells
Breast Myoepithelial cells
Vagina Squamous epithelial cells
Cervix Squamous epithelial cells
N/A
Cervix Glandular cells
Endometrium 1 Glandular cells
Endometrium 1 Cells in endometrial stroma
Endometrium 2 Glandular cells
Endometrium 2 Cells in endometrial stroma
Fallopian tube Glandular cells
Ovary Follicle cells
N/A
N/A
N/A
Ovary Ovarian stroma cells
Placenta Trophoblastic cells
N/A
Placenta Decidual cells
N/A
N/A
Placenta Cytotrophoblasts
N/A
N/A
Placenta Endothelial cells
N/A
N/A
Placenta Hofbauer cells
N/A
N/A
Placenta Syncytiotrophoblasts - cell body
N/A
N/A
Placenta Syncytiotrophoblasts - microvilli
N/A
N/A
Muscle tissues
Heart muscle Cardiomyocytes
Skeletal muscle Myocytes
Smooth muscle Smooth muscle cells
Connective & Soft tissue
Adipose tissue Adipocytes
Soft tissue 1 Peripheral nerve
N/A
N/A
Soft tissue 1 Chondrocytes
N/A
N/A
N/A
Soft tissue 1 Fibroblasts
Soft tissue 2 Fibroblasts
Soft tissue 2 Chondrocytes
N/A
Soft tissue 2 Peripheral nerve
Skin
Skin 1 Arrector pili muscle cells
N/A
N/A
Skin 1 Cells in basal layer
N/A
N/A
Skin 1 Cells in corneal layer
N/A
N/A
Skin 1 Cells in granular layer
N/A
N/A
Skin 1 Cells in spinous layer
N/A
N/A
Skin 1 Eccrine glands
N/A
N/A
Skin 1 Endothelial cells
N/A
N/A
Skin 1 Extracellular matrix
N/A
N/A
Skin 1 Fibroblasts
N/A
Skin 1 Fibrohistiocytic cells
N/A
N/A
Skin 1 Keratinocytes
N/A
Skin 1 Langerhans
N/A
Skin 1 Langerhans cells
N/A
N/A
Skin 1 Lymphocytes
N/A
N/A
Skin 1 Melanocytes
Skin 1 Vascular mural cells
N/A
N/A
Skin 2 Cells in basal layer
N/A
N/A
Skin 2 Cells in corneal layer
N/A
N/A
Skin 2 Cells in granular layer
N/A
N/A
Skin 2 Cells in spinous layer
N/A
N/A
Skin 2 Endothelial cells
N/A
N/A
Skin 2 Epidermal cells
N/A
Skin 2 Extracellular matrix
N/A
N/A
Skin 2 Fibrohistiocytic cells
N/A
N/A
Skin 2 Hair follicles
N/A
N/A
Skin 2 Langerhans cells
N/A
N/A
Skin 2 Lymphocytes
N/A
N/A
Skin 2 Melanocytes
N/A
N/A
Skin 2 Vascular mural cells
N/A
N/A
Bone marrow & Lymphoid tissues
Appendix Glandular cells
Appendix Lymphoid tissue
Bone marrow Hematopoietic cells
Lymph node Germinal center cells
N/A
Lymph node Non-germinal center cells
Tonsil Germinal center cells
Tonsil Non-germinal center cells
Tonsil Squamous epithelial cells
Spleen Cells in white pulp
Spleen Cells in red pulp
 
Staining summaryi

Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.

HPA001032 Most normal cells showed strong nuclear positivity. Hepatocytes and cells in CNS were generally negative.
HPA027214 Most of the normal tissues displayed moderate to strong nuclear and/or cytoplasmic positivity. Liver, kidney, adrenal glandular, muscle cells, lymphoid reaction center cells and CNS tissues were negative.
CAB037024 Normal tissues displayed moderate to strong nuclear staining with additional cytoplasmic and membranous positivity in a few tissues.

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