On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.
Scroll down to view mRNA expression data in more detail.
HPA Brain:
1.1
nTPM
FANTOM5:
0.0
Scaled Tags Per Million
CEREBELLUM - SINGLE NUCLEI RNA EXPRESSIONi
RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).
- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon
- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.
SINGLE NUCLEI BRAIN - CEREBELLUM, NEURONSi
RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).
- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon
- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.
Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter:0
Cluster
Cell type
Expression (nCPM)
c-1
Granular cells (VGLUT1) ETV
c-2
Granular cells (VGLUT1) ETV
c-3
Granular cells (VGLUT1) ETV
c-4
Granular cells (VGLUT1) ETV
c-5
Granular cells (VGLUT1) ETV
c-6
Granular cells (VGLUT1) ETV
c-7
MLI1 Inhibitory (GAD1/2) TF...
c-8
MLI2 Inhibitory (GAD1/2) TF...
c-9
MLI1 Inhibitory (GAD1/2) TF...
c-10
DCN Inhibitory (GAD1/2) NXP...
c-11
DCN Excitatory (VGLUT2)
c-12
DCN Inhibitory (GAD1/2) FOX
c-13
UBC Excitatory (VGLUT1) LMX...
c-14
Golgi Cells Inhibitory (GAD...
c-15
DCN Inhibitory (GAD1/2) ROR...
c-16
Purkinje cells (GAD1/2) SLC...
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview
SINGLE NUCLEI BRAIN - CEREBELLUM, NON-NEURONALi
RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).
- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon
- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.
Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter:0
Cluster
Cell type
Expression (nCPM)
c-1
Microglia
c-2
Oligodendrocytes
c-3
Astrocytes
c-4
Oligodendrocyte progenitor ...
c-5
Oligodendrocytes
c-6
Oligodendrocytes
c-7
Bergmann glia
c-8
Oligodendrocytes
c-9
Oligodendrocytes
c-10
Bergmann glia
c-11
Oligodendrocytes
c-12
Oligodendrocyte progenitor ...
c-13
Bergmann glia
c-14
Astrocytes
c-15
Astrocytes
c-16
Astrocytes
c-17
Fibroblasts
c-18
Oligodendrocytes
c-19
Macrophages
c-20
Vascular endothelial cells
c-21
Pericytes
c-22
T-cells
c-23
NK-cells
c-24
Immature oligodendrocytes
c-25
Vascular smooth muscle cell
c-26
Ependymal cells
c-27
T cells & NK cells
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview
CEREBELLUM - Annotated protein expression
Pending normal tissue analysis
CEREBELLUM - HPA Brain Stereo-seq
CEREBELLUM - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
1.1
Sample id
Sample description
nTPM
Cerebellar cortex nTPM: 1.0
1788
Male, age 55, unknown
1.6
1769
Male, age 76, right hemisphere
1.2
1774
Male, age 80, left hemisphere
1.0
2003
Female, age 85, right hemisphere
1.0
2006
Male, age 61, right hemisphere
1.0
2055
Female, age 91, right hemisphere
0.9
2101
Male, age 74, right hemisphere
0.9
1768
Female, age 72, unknown
0.8
Cerebellar nuclei nTPM: 1.0
2175
Male, age 61, right hemisphere
1.3
2882
Male, age 76, left hemisphere
1.3
2318
Male, age 74, left hemisphere
1.0
1871
Male, age 74, unknown
0.9
2005
Male, age 80, left hemisphere
0.9
2177
Female, age 85, both hemispheres
0.9
1966
Female, age 91, left hemisphere
0.8
1879
Male, age 55, unknown
0.7
2783
Female, age 72, unknown
0.7
Cerebellar white matter nTPM: 0.9
1931
Female, age 91, left hemisphere
1.1
2174
Male, age 61, right hemisphere
1.0
1837
Male, age 76, left hemisphere
0.9
1864
Male, age 80, left hemisphere
0.9
2105
Male, age 74, right hemisphere
0.9
2773
Female, age 85, right hemisphere
0.9
Flocculonodular lobe nTPM: 1.1
1771
Male, age 80, left hemisphere
1.4
1792
Male, age 74, unknown
1.2
1765
Male, age 55, unknown
1.1
1835
Female, age 85, right hemisphere
1.1
1767
Male, age 76, left hemisphere
0.9
2176
Female, age 91, right hemisphere
0.9
2004
Male, age 61, right hemisphere
0.8
Vermis nTPM: 0.9
1825
Male, age 74, unknown
1.3
1778
Female, age 91, left hemisphere
1.1
2834
Male, age 80, left hemisphere
1.1
1988
Female, age 85, left hemisphere
1.0
2460
Male, age 61, both hemispheres
1.0
1766
Male, age 55, unknown
0.9
1751
Male, age 74, right hemisphere
0.8
1770
Male, age 76, left hemisphere
0.8
1928
Female, age 72, unknown
0.5
CEREBELLUM - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
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