The exploration of the human proteome has revealed many uncharacterized proteins with very interesting distributions in tissues and cells. Among them are many receptor proteins with unknown functions and predominant expression in the brain, including the orphan receptor GPR151...Read more

In this movie Professor Tomas Hökfelt (Karolinska Institutet) takes you on a journey to the areas of the brain affected by Alzheimer's disease...Read more

Cilia and flagella are fascinating organelles that can be seen as thin membrane-bound projections extending from the body of various cell types. Most well-known are the flagella of sperm cells and the motile cilia that are present in epithelial cells of the lungs and fallopian tubes, as well as ependymal cells of the brain ventricles. These types of cilia mediate movement. However, there is a third type of cilia, which are non-motile and present in most human cell types, referred to as primary cilia...Read more

In December 2019 an outbreak of the novel infectious virus SARS-CoV2 occurred and immense research is currently going on to contain the virus. Being a novel virus it is highly important to learn how the immune system has responded to the past viral infections in particular to the coronavirus family...Read more

To fold or to degrade? Proteins have to be folded to its native structure in order to perform its designated tasks and a failure to do so leads to deleterious effects. Chaperones as the name suggest prevents improper interactions and ensures proper functioning of the proteome...Read more