Soon it is time for the summer holiday! But before you can take that well-deserved vacation there are many things that have to be done. Speaking of the need of multitasking, that is what many proteins have to do every day to keep your body up and running...Read more
The centrosome is a non-membranous subcellular structure composed of a mother and daughter centriole. The mother centriole function as the assembly point for the primary cilium, a microtubule-based sensory organelle, which is involved in signal transduction...Read more
SUN2 (Sad1 and UNC84 domain containing 2), found in the nuclear membrane of cells, is an essential protein for many cellular processes. SUN plays a large role in the organization of multi-nucleated muscle cells, and dysregulation of SUN can cause muscular dystrophy among other diseases...Read more
Autophagosomes play a crucial role in recycling, by degrading cellular components and providing building blocks for renewal och cell components. Last year, we published a post about autophagy, which was the subject of the 2016 Nobel Prize in Physiology and Medicine.
We show, for the first time, images of HPA antibodies that co-localize with the autophagosomes. These membrane bound vesicles are involved in degradation of cellular constituents through a process called autophagy. The protein detected is localized to the autophagosomes (green) in SH-SY5Y cells, a human neuroblastoma cell line from neural tissue...Read more
Diurnal cycle influence biological processes in all organisms, on a molecular level, through regulators of the circadian clock. The Nuclear factor interleukin-3-regulated protein is a component of the circadian clock in humans that also fluctuates with the seasons. The Human Protein Atlas team has stained in A-431 cells NFIL3 (green) in nuclear bodies with DNA (blue) and microtubules (red)...Read more
September 14, 2019 - September 18, 2019
HPA Presence at HUPO 2019
Several researchers from HPA will participate in HUPO 2019, both with lectures and during poster sessions.
September 22, 2019 - September 26, 2019
Mathias Uhlen holds the PEACe keynote lecture, titled "The Human Secretome Project - generation of all human secreted proteins in mammalian cell cultures".
September 5, 2019