DLX6

GENERAL INFORMATION

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Gene name

DLX6

Gene description

Distal-less homeobox 6

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (endometrium, placenta, testis)
GTEx:Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in testis, endometrium and placenta. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Presumed off target binding observed and disregarded. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA030608
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (endometrium, placenta, testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression



GENE INFORMATION

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Gene name

DLX6

Synonyms

Description

Distal-less homeobox 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. This family is comprised of at least 6 different members that encode proteins with roles in forebrain and craniofacial development. This gene is in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q21.3

Chromosome location (bp)

97005548 - 97011039

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000006377 (version 78.38)

Entrez gene

1750

UniProt

P56179 (UniProt - Evidence at transcript level)

neXtProt

NX_P56179

Antibodypedia

DLX6 antibodies


PROTEIN BROWSER

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ENST00000518156
 
ENST00000555308
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DLX6-001 ENSP00000428480
ENST00000518156
P56179
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Show » Show » 293 32.6 No 0
DLX6-003 ENSP00000451635
ENST00000555308
G3V471
Show all »
Show » Show » 165 18.6 No 0