PIGQ

GENERAL INFORMATION

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Gene name

PIGQ

Gene description

Phosphatidylinositol glycan anchor biosynthesis, class Q

Protein class

Enzymes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic and membranous expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA039105 , HPA039828
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PIGQ (HGNC Symbol)

Synonyms

GPI1, hGPI1

Description

Phosphatidylinositol glycan anchor biosynthesis, class Q (HGNC Symbol)

Entrez gene summary

This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

566995 - 584136

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000007541 (version 78.38)

Entrez gene

9091

UniProt

Q9BRB3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BRB3

Antibodypedia

PIGQ antibodies


PROTEIN BROWSER

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ENST00000026218
 
ENST00000293874
 
ENST00000321878
 
ENST00000409439
 
ENST00000409527
 
ENST00000422307
 
ENST00000439574
 
ENST00000470411
 
ENST00000540241
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PIGQ-001 ENSP00000326674
ENST00000321878
Q9BRB3
Show all »
Show » Show » 581 65.3 No 7
PIGQ-002 ENSP00000026218
ENST00000026218
Q9BRB3
Show all »
Show » Show » 760 84.1 No 8
PIGQ-004 ENSP00000386760
ENST00000409527
Q9BRB3
Show all »
Show » Show » 581 65.3 No 7
PIGQ-005 ENSP00000386554
ENST00000409439
B8ZZC7
Show all »
Show » 251 27.5 No 1
PIGQ-006 ENSP00000413753
ENST00000422307
B8ZZ31
Show all »
Show » 314 34.4 No 2
PIGQ-007 ENSP00000387820
ENST00000439574
B8ZZ29
Show all »
Show » 112 12.5 No 0
PIGQ-009 ENSP00000439650
ENST00000470411
Q9BRB3
Show all »
Show » Show » 299 32.5 No 1
PIGQ-011 ENSP00000293874
ENST00000293874
J3QTH6
Show all »
Show » 148 16.5 No 0
PIGQ-014 ENSP00000439374
ENST00000540241
H0YFM9
Show all »
Show » Show » 139 16.2 No 1