SNX1

GENERAL INFORMATION

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Gene name

SNX1

Gene description

Sorting nexin 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA047373
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SNX1 (HGNC Symbol)

Synonyms

HsT17379, MGC8664, SNX1A, Vps5

Description

Sorting nexin 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

15

Cytoband

q22.31

Chromosome location (bp)

64094123 - 64146090

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000028528 (version 78.38)

Entrez gene

6642

UniProt

Q13596 (UniProt - Evidence at protein level)

neXtProt

NX_Q13596

Antibodypedia

SNX1 antibodies


PROTEIN BROWSER

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ENST00000261889
 
ENST00000558040
 
ENST00000559061
 
ENST00000559844
 
ENST00000560829
 
ENST00000560861
 
ENST00000561026
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNX1-001 ENSP00000453785
ENST00000559844
Q13596
Show all »
Show » Show » 522 59.1 No 0
SNX1-002 ENSP00000453567
ENST00000561026
Q13596
Show all »
Show » Show » 457 51.8 No 0
SNX1-003 ENSP00000261889
ENST00000261889
Q13596
Show all »
Show » Show » 557 63.1 No 0
SNX1-004 ENSP00000452651
ENST00000560829
H0YK42
Show all »
Show » Show » 304 35.6 No 0
SNX1-008 ENSP00000452652
ENST00000559061
Show » 19 2.2 No 0
SNX1-009 ENSP00000452668
ENST00000558040
H0YK58
Show all »
Show » Show » 128 13.6 No 0
SNX1-010 ENSP00000452931
ENST00000560861
H0YKT3
Show all »
Show » Show » 70 8.4 No 0