HOXC8

GENERAL INFORMATION

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Gene name

HOXC8

Gene description

Homeobox C8

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (smooth muscle)
GTEx:Tissue enhanced (fallopian tube)

Protein evidence

Evidence at protein level

Protein localization

Nuclear and cytoplasmic expression in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA028911 , CAB037020
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (smooth muscle)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (fallopian tube)

Organ

Expression



GENE INFORMATION

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Gene name

HOXC8 (HGNC Symbol)

Synonyms

HOX3, HOX3A

Description

Homeobox C8 (HGNC Symbol)

Entrez gene summary

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

54009106 - 54012362

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000037965 (version 78.38)

Entrez gene

3224

UniProt

P31273 (UniProt - Evidence at protein level)

neXtProt

NX_P31273

Antibodypedia

HOXC8 antibodies


PROTEIN BROWSER

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ENST00000040584
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HOXC8-001 ENSP00000040584
ENST00000040584
P31273
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