PI4K2B

GENERAL INFORMATION

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Gene name

PI4K2B

Gene description

Phosphatidylinositol 4-kinase type 2 beta

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

A majority of normal tissues displayed moderate to strong cytoplasmic immunoreactivity, in some cases with a granular pattern. Strongest positivity was observed in glandular epithelia of the gastrointestinal tract and in lymphoid tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA004099
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PI4K2B (HGNC Symbol)

Synonyms

FLJ11105, PI4KIIB, PIK42B

Description

Phosphatidylinositol 4-kinase type 2 beta (HGNC Symbol)

Entrez gene summary

Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate (PIP), an immediate precursor of several important signaling and scaffolding molecules. PIP itself may also have direct functional and structural roles. PI4K2B is a primarily cytosolic PI4K that is recruited to membranes, where it stimulates phosphatidylinositol 4,5-bisphosphate synthesis (Wei et al., 2002 [PubMed 12324459]).[supplied by OMIM, Jun 2008]

Chromosome

4

Cytoband

p15.2

Chromosome location (bp)

25160641 - 25279092

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000038210 (version 78.38)

Entrez gene

55300

UniProt

Q8TCG2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TCG2

Antibodypedia

PI4K2B antibodies


PROTEIN BROWSER

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ENST00000264864
 
ENST00000512921
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PI4K2B-001 ENSP00000264864
ENST00000264864
Q8TCG2
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Show » Show » 481 54.7 No 0
PI4K2B-003 ENSP00000423373
ENST00000512921
G5E9Z4
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Show » Show » 385 44.8 No 0