HHAT

GENERAL INFORMATION

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Gene name

HHAT

Gene description

Hedgehog acyltransferase

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Moderate to strong cytoplasmic positivity with a granular pattern was observed in glandular cells, hepatocyes, renal tubules, placental trophoblasts, testis, neuronal cells and heart muscle. A subset of cells in spleen and bone marrow were strongly stained. Erythrocytes were stained. Remaining tissues were mainly negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA016462
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

HHAT (HGNC Symbol)

Synonyms

FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn

Description

Hedgehog acyltransferase (HGNC Symbol)

Entrez gene summary

'Skinny hedgehog' (SKI1) encodes an enzyme that acts within the secretory pathway to catalyze amino-terminal palmitoylation of 'hedgehog' (see MIM 600725).[supplied by OMIM, Jul 2002]

Chromosome

1

Cytoband

q32.2

Chromosome location (bp)

210328252 - 210676296

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000054392 (version 78.38)

Entrez gene

55733

UniProt

Q5VTY9 (UniProt - Evidence at protein level)

neXtProt

NX_Q5VTY9

Antibodypedia

HHAT antibodies


PROTEIN BROWSER

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ENST00000261458
 
ENST00000367009
 
ENST00000367010
 
ENST00000413764
 
ENST00000426968
 
ENST00000537898
 
ENST00000541565
 
ENST00000545154
 
ENST00000545781
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HHAT-001 ENSP00000261458
ENST00000261458
Q5VTY9
Show all »
Show » Show » 493 57.3 No >9
HHAT-002 ENSP00000355976
ENST00000367009
B1AK61
Show all »
Show » Show » 183 20.8 No 4
HHAT-003 ENSP00000413399
ENST00000426968
A0A075B6R5
Show all »
Show » 207 24.2 Yes 4
HHAT-004 ENSP00000355977
ENST00000367010
Q5VTY9
Show all »
Show » Show » 493 57.3 No >9
HHAT-201 ENSP00000416845
ENST00000413764
Q5VTY9
Show all »
Show » Show » 493 57.3 No >9
HHAT-202 ENSP00000442625
ENST00000537898
Q5VTY9
Show all »
Show » Show » 428 49.9 No >9
HHAT-203 ENSP00000444995
ENST00000541565
Q5VTY9
Show all »
Show » Show » 356 41.1 No 8
HHAT-204 ENSP00000438468
ENST00000545154
Q5VTY9
Show all »
Show » Show » 494 57 No >9
HHAT-205 ENSP00000439229
ENST00000545781
Show » 82 9.3 No 0