GDI2

GENERAL INFORMATION

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Gene name

GDI2

Gene description

GDP dissociation inhibitor 2

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Data reliability

Supportive based on 2 antibodies.
HPA049290 , HPA057668
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Tonsil

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

GDI2 (HGNC Symbol)

Synonyms

RABGDIB

Description

GDP dissociation inhibitor 2 (HGNC Symbol)

Entrez gene summary

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

p15.1

Chromosome location (bp)

5765223 - 5842132

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000057608 (version 78.38)

Entrez gene

2665

UniProt

P50395 (UniProt - Evidence at protein level)

neXtProt

NX_P50395

Antibodypedia

GDI2 antibodies


PROTEIN BROWSER

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ENST00000380127
 
ENST00000380181
 
ENST00000380191
 
ENST00000418688
 
ENST00000447751
 
ENST00000456041
 
ENST00000608581
 
ENST00000609712
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GDI2-001 ENSP00000369538
ENST00000380191
P50395
Show all »
Show » Show » 445 50.7 No 0
GDI2-002 ENSP00000369528
ENST00000380181
P50395
Show all »
Show » Show » 400 45.6 No 0
GDI2-003 ENSP00000387565
ENST00000447751
Q5SX91
Show all »
Show » Show » 203 23.1 No 0
GDI2-004 ENSP00000394177
ENST00000418688
Q5SX86
Show all »
Show » Show » 155 17.8 No 0
GDI2-005 ENSP00000401733
ENST00000456041
Q5SX87
Show all »
Show » Show » 263 29.9 No 0
GDI2-007 ENSP00000369470
ENST00000380127
Q5SX90
Show all »
Show » Show » 148 16.8 No 0
GDI2-008 ENSP00000476707
ENST00000608581
V9GYF8
Show all »
Show » Show » 130 14.9 No 0
GDI2-009 ENSP00000476832
ENST00000609712
V9GYJ7
Show all »
Show » Show » 126 14.2 No 0