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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:6.5 nTPM
HPA:6.5 nTPM
GTEx:3.7 nTPM
FANTOM5:35.2 Scaled Tags Per Million
Pig:26.9 nTPM
Mouse:33.4 nTPM
Allen mouse:2.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 6.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 4.7
2219 Male, age 76, both hemispheres 6.0
2828 Female, age 72, unknown 6.0
2019 Male, age 18, unknown 5.6
2411 Female, age 72, unknown 5.6
1827 Male, age 72, unknown 5.5
2666 Male, age 74, left hemisphere 3.9
1830 Male, age 51, unknown 3.8
1833 Male, age 53, unknown 3.7
1870 Female, age 42, unknown 3.5
2586 Male, age 75, left hemisphere 2.9
Dorsal raphe nucleus
nTPM: 4.0
2047 Male, age 72, unknown 5.0
1828 Male, age 53, unknown 4.5
2750 Male, age 76, both hemispheres 4.1
2298 Female, age 72, unknown 3.3
2016 Female, age 72, unknown 3.0
Inferior colliculus
nTPM: 4.5
2097 Female, age 72, unknown 5.9
1890 Male, age 53, unknown 4.5
1848 Female, age 42, unknown 4.1
2849 Male, age 72, unknown 3.3
Median raphe nucleus
nTPM: 6.1
2220 Male, age 76, midline 6.1
Pedunculopontine tegmental nucleus
nTPM: 3.5
2334 Male, age 80, both hemispheres 4.4
1921 Female, age 85, both hemispheres 3.2
2338 Male, age 61, both hemispheres 2.8
Periaquaductal grey, anterior
nTPM: 6.5
1947 Male, age 18, unknown 7.4
1795 Male, age 51, unknown 6.5
2502 Female, age 75, unknown 5.8
Periaquaductal grey, dorsal
nTPM: 2.9
2850 Male, age 76, both hemispheres 3.4
1840 Male, age 53, unknown 2.9
2464 Female, age 72, unknown 2.6
1831 Male, age 72, unknown 2.5
Periaquaductal grey, lateral
nTPM: 3.2
2272 Male, age 74, both hemispheres 4.1
2140 Male, age 76, both hemispheres 2.9
2053 Male, age 18, unknown 2.5
Pretectal area
nTPM: 4.9
2007 Male, age 72, unknown 8.0
1816 Male, age 51, unknown 7.3
1815 Male, age 53, unknown 7.2
1817 Female, age 42, unknown 6.3
1944 Female, age 72, unknown 5.8
2407 Male, age 75, both hemispheres 3.9
2224 Female, age 72, unknown 3.5
2825 Male, age 18, unknown 3.4
2273 Male, age 74, both hemispheres 3.0
2316 Male, age 76, right hemisphere 2.9
2667 Female, age 75, unknown 2.9
Red nucleus
nTPM: 4.3
2785 Male, age 18, unknown 6.5
2503 Female, age 72, unknown 5.5
2584 Male, age 75, left hemisphere 5.1
2227 Male, age 72, unknown 4.6
1821 Female, age 72, unknown 4.4
1954 Female, age 42, unknown 4.4
2725 Female, age 75, unknown 4.3
1904 Male, age 53, unknown 4.0
1865 Male, age 51, unknown 3.7
2823 Male, age 76, right hemisphere 3.6
2588 Male, age 74, left hemisphere 2.9
2769 Male, age 72, unknown 2.9
Substantia nigra
nTPM: 4.3
2590 Female, age 75, unknown 5.8
1889 Female, age 72, unknown 5.0
1916 Female, age 42, unknown 5.0
1941 Male, age 53, unknown 4.7
2583 Male, age 75, right hemisphere 4.7
2665 Male, age 74, both hemispheres 4.6
1851 Male, age 51, unknown 4.3
2409 Female, age 72, unknown 3.3
2241 Male, age 72, unknown 3.2
2699 Male, age 18, unknown 2.7
Superior colliculus
nTPM: 3.9
2087 Female, age 72, unknown 5.4
2587 Male, age 74, left hemisphere 5.2
2668 Female, age 75, unknown 5.1
1796 Male, age 53, unknown 4.4
2261 Male, age 18, unknown 4.0
1913 Female, age 42, unknown 3.5
1839 Male, age 51, unknown 3.3
1895 Male, age 76, right hemisphere 3.1
1995 Male, age 72, unknown 2.9
2664 Male, age 75, both hemispheres 2.4
Ventral tegmental area
nTPM: 4.2
2410 Female, age 72, unknown 6.0
2218 Male, age 76, both hemispheres 5.6
1942 Male, age 51, unknown 4.0
2223 Female, age 72, unknown 4.0
1915 Female, age 42, unknown 3.7
2021 Male, age 53, unknown 1.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 3.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 3.7
Samples: 139

Max nTPM: 7.8
Min nTPM: 0.1
Std nTPM: 1.2
Median nTPM: 3.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 7.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 7.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 6.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 6.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 6.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 6.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 6.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 6.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 5.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 5.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 5.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 5.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 5.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 5.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 5.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 5.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 5.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 5.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 5.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 5.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 5.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 5.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 4.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 4.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 4.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 4.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 4.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 4.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 4.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 4.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 4.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 4.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 4.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 4.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 4.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 4.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 4.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 4.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 4.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 4.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 4.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 4.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 4.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 4.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 4.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 4.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 4.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 4.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 4.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 4.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 4.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 4.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 3.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 3.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 3.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 3.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 3.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 3.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 3.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 3.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 3.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 3.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 3.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 3.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 3.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 3.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 3.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 3.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 3.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 3.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 3.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 3.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 3.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 3.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 3.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 3.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 3.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 3.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 3.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 3.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 3.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 3.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 3.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 3.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 3.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 3.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 3.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 3.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 3.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 3.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 3.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 3.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 3.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 3.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 3.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 3.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 3.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 3.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 3.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 3.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 2.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 2.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 2.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 2.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 2.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 2.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 2.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 2.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 2.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 2.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 2.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 2.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 2.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 2.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 2.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 2.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 2.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 2.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 2.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 2.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 0.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 0.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 35.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 35.2
FF:10158-103A5 76 years, female 35.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 26.9
Pig sample Sample description nTPM
Midbrain
nTPM: 26.0
Samples: 4

Max nTPM: 28.8
Min nTPM: 23.9
Sample A Female 26.5
Sample B Female 24.9
Sample C Male 28.8
Sample D Male 23.9
Periaqueductal gray
nTPM: 21.2
Samples: 3

Max nTPM: 22.0
Min nTPM: 20.7
Sample B Female 22.0
Sample C Male 20.7
Sample D Male 20.8
Substantia nigra
nTPM: 24.8
Samples: 4

Max nTPM: 27.5
Min nTPM: 21.9
Sample A Female 27.5
Sample B Female 21.9
Sample C Male 25.4
Sample D Male 24.5
Superior colliculi
nTPM: 26.9
Samples: 4

Max nTPM: 30.9
Min nTPM: 24.4
Sample A Female 24.4
Sample B Female 26.2
Sample C Male 30.9
Sample D Male 26.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 33.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 33.4
Samples: 4

Max nTPM: 36.3
Min nTPM: 27.7
Sample A Male 27.7
Sample B Male 36.2
Sample C Female 36.3
Sample D Female 33.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.7
77620265 Antisense, RP_070129_05_E04, Mouse strain C57BL/6J (56 days, male) 2.7

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