ZDHHC8

GENERAL INFORMATION

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Gene name

ZDHHC8

Gene description

Zinc finger, DHHC-type containing 8

Protein class

Enzymes
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Hepatocytes, tubules of the kidney, a sub-set of basal cells in testis, neuropil and neuronal cells in CNS showed moderate to strong cytoplasmic positivity. Remaining normal cells were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA003422
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ZDHHC8 (HGNC Symbol)

Synonyms

KIAA1292, ZNF378

Description

Zinc finger, DHHC-type containing 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.[provided by RefSeq, May 2010]

Chromosome

22

Cytoband

q11.21

Chromosome location (bp)

20129456 - 20148007

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000099904 (version 78.38)

Entrez gene

29801

UniProt

Q9ULC8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9ULC8

Antibodypedia

ZDHHC8 antibodies


PROTEIN BROWSER

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ENST00000320602
 
ENST00000334554
 
ENST00000405930
 
ENST00000436518
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZDHHC8-001 ENSP00000334490
ENST00000334554
Q9ULC8
Show all »
Show » Show » 765 81.4 No 4
ZDHHC8-002 ENSP00000384716
ENST00000405930
Q9ULC8
Show all »
Show » Show » 778 83.2 No 4
ZDHHC8-003 ENSP00000317804
ENST00000320602
Q9ULC8
Show all »
Show » Show » 673 71.2 No 2
ZDHHC8-004 ENSP00000412807
ENST00000436518
C9JVM2
Show all »
Show » Show » 180 20.4 No 2