TBL1X

GENERAL INFORMATION

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Gene name

TBL1X

Gene description

Transducin (beta)-like 1X-linked

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear and nuclear membrane expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
CAB005363
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

TBL1X (HGNC Symbol)

Synonyms

EBI, TBL1

Description

Transducin (beta)-like 1X-linked (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq, Nov 2008]

Chromosome

X

Cytoband

Chromosome location (bp)

9463295 - 9719743

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101849 (version 78.38)

Entrez gene

6907

UniProt

O60907 (UniProt - Evidence at protein level)

neXtProt

NX_O60907

Antibodypedia

TBL1X antibodies


PROTEIN BROWSER

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ENST00000217964
 
ENST00000380961
 
ENST00000407597
 
ENST00000415293
 
ENST00000422314
 
ENST00000424279
 
ENST00000441088
 
ENST00000452824
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TBL1X-001 ENSP00000397878
ENST00000452824
C9J5F9
Show all »
Show » 80 8.8 No 0
TBL1X-002 ENSP00000370348
ENST00000380961
O60907
Show all »
Show » Show » 526 57 No 0
TBL1X-003 ENSP00000217964
ENST00000217964
O60907
Show all »
Show » Show » 577 62.5 No 0
TBL1X-004 ENSP00000402923
ENST00000441088
C9JP56
Show all »
Show » 59 6.3 No 0
TBL1X-005 ENSP00000407069
ENST00000415293
C9JYQ8
Show all »
Show » Show » 75 8.2 No 0
TBL1X-006 ENSP00000415508
ENST00000422314
C9JCW3
Show all »
Show » Show » 45 5 No 0
TBL1X-201 ENSP00000385988
ENST00000407597
O60907
Show all »
Show » Show » 577 62.5 No 0
TBL1X-202 ENSP00000394097
ENST00000424279
O60907
Show all »
Show » Show » 526 57 No 0