CHRDL1

GENERAL INFORMATION

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Gene name

CHRDL1

Gene description

Chordin-like 1

Protein class

Disease related genes
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enhanced (endometrium)

Protein evidence

Evidence at protein level

Protein localization

Expression mainly in kidney and fallopian tube.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA000226 , HPA000250
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Endometrium



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (endometrium)

Organ

Expression



GENE INFORMATION

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Gene name

CHRDL1 (HGNC Symbol)

Synonyms

CHL, MGC1, NRLN1

Description

Chordin-like 1 (HGNC Symbol)

Entrez gene summary

This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]

Chromosome

X

Cytoband

q23

Chromosome location (bp)

110673856 - 110795819

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101938 (version 78.38)

Entrez gene

91851

UniProt

Q9BU40 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BU40

Antibodypedia

CHRDL1 antibodies


PROTEIN BROWSER

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ENST00000372042
 
ENST00000372045
 
ENST00000394797
 
ENST00000444321
 
ENST00000482160
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHRDL1-001 ENSP00000361115
ENST00000372045
Q9BU40
Show all »
Show » Show » 450 51.2 Yes 0
CHRDL1-002 ENSP00000361112
ENST00000372042
Q9BU40
Show all »
Show » Show » 458 52.3 Yes 0
CHRDL1-004 ENSP00000378276
ENST00000394797
Q9BU40
Show all »
Show » Show » 456 52 Yes 0
CHRDL1-005 ENSP00000418443
ENST00000482160
Q9BU40
Show all »
Show » Show » 378 43.5 Yes 0
CHRDL1-006 ENSP00000399739
ENST00000444321
Q9BU40
Show all »
Show » Show » 457 52.2 Yes 0