HMOX2

GENERAL INFORMATION

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Gene name

HMOX2

Gene description

Heme oxygenase (decycling) 2

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

17
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA040611 , CAB025464
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Gallbladder

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

HMOX2 (HGNC Symbol)

Synonyms

HO-2

Description

Heme oxygenase (decycling) 2 (HGNC Symbol)

Entrez gene summary

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

4474690 - 4510347

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103415 (version 78.38)

Entrez gene

3163

UniProt

P30519 (UniProt - Evidence at protein level)

neXtProt

NX_P30519

Antibodypedia

HMOX2 antibodies


PROTEIN BROWSER

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ENST00000219700
 
ENST00000398595
 
ENST00000406590
 
ENST00000414777
 
ENST00000458134
 
ENST00000570445
 
ENST00000570622
 
ENST00000570646
 
ENST00000572812
 
ENST00000574466
 
ENST00000575051
 
ENST00000575120
 
ENST00000575129
 
ENST00000576827
 
ENST00000613539
 
ENST00000619528
 
ENST00000619913
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HMOX2-001 ENSP00000459214
ENST00000570646
P30519
Show all »
Show » Show » 316 36 No 1
HMOX2-002 ENSP00000394103
ENST00000458134
P30519
Show all »
Show » Show » 316 36 No 1
HMOX2-003 ENSP00000381595
ENST00000398595
P30519
Show all »
Show » Show » 316 36 No 1
HMOX2-004 ENSP00000219700
ENST00000219700
P30519
Show all »
Show » Show » 316 36 No 1
HMOX2-005 ENSP00000458797
ENST00000575051
I3L1F5
Show all »
Show » Show » 238 27.7 No 0
HMOX2-006 ENSP00000460926
ENST00000575120
P30519
Show all »
Show » Show » 287 32.8 No 1
HMOX2-007 ENSP00000461428
ENST00000574466
I3L1G7
Show all »
Show » Show » 131 15.2 No 0
HMOX2-008 ENSP00000459445
ENST00000572812
I3L276
Show all »
Show » Show » 110 12.6 No 0
HMOX2-009 ENSP00000458824
ENST00000576827
I3L1G7
Show all »
Show » Show » 131 15.2 No 0
HMOX2-010 ENSP00000460992
ENST00000575129
I3L463
Show all »
Show » Show » 132 15.3 No 0
HMOX2-011 ENSP00000458592
ENST00000570445
I3L159
Show all »
Show » Show » 229 26.6 No 0
HMOX2-012 ENSP00000459203
ENST00000570622
Show » Show » 110 12.8 No 0
HMOX2-201 ENSP00000385100
ENST00000406590
P30519
Show all »
Show » Show » 316 36 No 1
HMOX2-202 ENSP00000391637
ENST00000414777
P30519
Show all »
Show » Show » 316 36 No 1
HMOX2-203 ENSP00000477572
ENST00000613539
I3L1F5
Show all »
Show » Show » 370 41.7 No 1
HMOX2-204 ENSP00000484423
ENST00000619528
P30519
Show all »
Show » Show » 316 36 No 1
HMOX2-205 ENSP00000484467
ENST00000619913
P30519
Show all »
Show » Show » 316 36 No 1