VIPR2

GENERAL INFORMATION

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Gene name

VIPR2

Gene description

Vasoactive intestinal peptide receptor 2

Protein class

G-protein coupled receptors
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Adipocytes, myoepithelial cells, fibroblasts, chondrocytes and basal cells in squamous epithelium showed strong cytoplasmic staining. Membranous positivity was observed in decidual cells, thyroid, fallopian tube, Leydig cells and muscle. Remaining normal tissues were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA062707
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Tonsil

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

VIPR2 (HGNC Symbol)

Synonyms

VPAC2, VPAC2R

Description

Vasoactive intestinal peptide receptor 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011]

Chromosome

7

Cytoband

q36.3

Chromosome location (bp)

159028175 - 159144957

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106018 (version 78.38)

Entrez gene

7434

UniProt

P41587 (UniProt - Evidence at protein level)

neXtProt

NX_P41587

Antibodypedia

VIPR2 antibodies


PROTEIN BROWSER

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ENST00000262178
 
ENST00000377633
 
ENST00000402066
 
ENST00000421760
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VIPR2-001 ENSP00000262178
ENST00000262178
P41587
Show all »
Show » Show » 438 49.5 Yes 7
VIPR2-002 ENSP00000384497
ENST00000402066
C9JCP7
Show all »
Show » Show » 579 64 Yes 7
VIPR2-003 ENSP00000366860
ENST00000377633
P41587
Show all »
Show » Show » 422 46.8 No 7
VIPR2-004 ENSP00000402690
ENST00000421760
E9PCR5
Show all »
Show » Show » 77 8.8 Yes 0