DNMBP

GENERAL INFORMATION

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Gene name

DNMBP

Gene description

Dynamin binding protein

Protein class

Cytoskeleton related proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

A subset of cells in prostate showed strong cytoplasmic staining. Rectum and stomach were moderately stained. Intercalated disc of heart muscle exhibited moderate membranous staining. Remaining tissues were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA037878
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

DNMBP (HGNC Symbol)

Synonyms

ARHGEF36, KIAA1010, Tuba

Description

Dynamin binding protein (HGNC Symbol)

Entrez gene summary

DNMBP belongs to the DBL (MIM 311030) family of guanine nucleotide exchange factors and plays a role in the regulation of cell junctions (Otani et al., 2006 [PubMed 17015620]).[supplied by OMIM, Mar 2008]

Chromosome

10

Cytoband

q24.2

Chromosome location (bp)

99875577 - 100009919

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107554 (version 78.38)

Entrez gene

23268

UniProt

Q6XZF7 (UniProt - Evidence at protein level)

neXtProt

NX_Q6XZF7

Antibodypedia

DNMBP antibodies


PROTEIN BROWSER

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ENST00000324109
 
ENST00000422692
 
ENST00000543621
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNMBP-001 ENSP00000315659
ENST00000324109
Q6XZF7
Show all »
Show » Show » 1577 177.3 No 0
DNMBP-002 ENSP00000409476
ENST00000422692
Q5SVK9
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Show » Show » 224 25.3 No 0
DNMBP-201 ENSP00000443657
ENST00000543621
Q6XZF7
Show all »
Show » Show » 823 93.5 No 0