BST1

GENERAL INFORMATION

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Gene name

BST1

Gene description

Bone marrow stromal cell antigen 1

Protein class

CD markers
Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Squamous epithelia, testis and smooth muscle displayed moderate cytoplasmic positivity. Remaining normal tissues were weakly positive or were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA050121
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Smooth muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

BST1 (HGNC Symbol)

Synonyms

CD157

Description

Bone marrow stromal cell antigen 1 (HGNC Symbol)

Entrez gene summary

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]

Chromosome

4

Cytoband

p15.32

Chromosome location (bp)

15702950 - 15738313

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000109743 (version 78.38)

Entrez gene

683

UniProt

Q10588 (UniProt - Evidence at protein level)

neXtProt

NX_Q10588

Antibodypedia

BST1 antibodies


PROTEIN BROWSER

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ENST00000265016
 
ENST00000382346
 
ENST00000505785
 
ENST00000514445
 
ENST00000514989
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BST1-001 ENSP00000265016
ENST00000265016
Q10588
Show all »
Show » Show » 318 35.7 Yes 0
BST1-002 ENSP00000371783
ENST00000382346
A6NC48
Show all »
Show » Show » 333 37.5 Yes 0
BST1-003 ENSP00000424761
ENST00000514989
Show » Show » 97 11 No 0
BST1-004 ENSP00000423357
ENST00000505785
Show » Show » 186 21 No 0
BST1-005 ENSP00000420925
ENST00000514445
H0Y8G4
Show all »
Show » Show » 155 17.6 No 0