DUSP16

GENERAL INFORMATION

? »

Gene name

DUSP16

Gene description

Dual specificity phosphatase 16

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA020326
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

DUSP16 (HGNC Symbol)

Synonyms

KIAA1700, MKP-7, MKP7

Description

Dual specificity phosphatase 16 (HGNC Symbol)

Entrez gene summary

This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010]

Chromosome

12

Cytoband

p13.2

Chromosome location (bp)

12474210 - 12562383

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111266 (version 78.38)

Entrez gene

80824

UniProt

Q9BY84 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BY84

Antibodypedia

DUSP16 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000228862
 
ENST00000298573
 
ENST00000539940
 
ENST00000541207
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DUSP16-001 ENSP00000298573
ENST00000298573
Q9BY84
Show all »
Show » Show » 665 73.1 No 0
DUSP16-002 ENSP00000441250
ENST00000541207
Show » 6 0.7 No 0
DUSP16-003 ENSP00000443039
ENST00000539940
F5H5X4
Show all »
Show » 25 2.8 No 0
DUSP16-201 ENSP00000228862
ENST00000228862
Q96QS2
Show all »
Show » Show » 143 16.1 No 0