ACAD10

GENERAL INFORMATION

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Gene name

ACAD10

Gene description

Acyl-CoA dehydrogenase family, member 10

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Subsets of leukocytes, hematopoietic cells, and cells in granular layer of cerebellum showed moderate cytoplasmic positivity. Moderate to strong membranous staining was observed in trophoblastic cells and in a fraction of glandular cells in epididymis and cells in renal tubules. Most remaining cells were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA067222
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ACAD10 (HGNC Symbol)

Synonyms

MGC5601

Description

Acyl-CoA dehydrogenase family, member 10 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Nov 2008]

Chromosome

12

Cytoband

q24.12

Chromosome location (bp)

111686056 - 111757107

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111271 (version 78.38)

Entrez gene

80724

UniProt

Q6JQN1 (UniProt - Evidence at transcript level)

neXtProt

NX_Q6JQN1

Antibodypedia

ACAD10 antibodies


PROTEIN BROWSER

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ENST00000313698
 
ENST00000455480
 
ENST00000507683
 
ENST00000514615
 
ENST00000515283
 
ENST00000549590
 
ENST00000552706
 
ENST00000552965
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACAD10-001 ENSP00000325137
ENST00000313698
Q6JQN1
Show all »
Show » Show » 1059 118.8 No 0
ACAD10-002 ENSP00000389813
ENST00000455480
Q6JQN1
Show all »
Show » Show » 1090 122.3 No 0
ACAD10-007 ENSP00000447561
ENST00000552706
F8W0Q4
Show all »
Show » Show » 226 25.2 No 0
ACAD10-009 ENSP00000421527
ENST00000514615
D6RFF6
Show all »
Show » 96 11.1 No 0
ACAD10-010 ENSP00000449097
ENST00000515283
F8VXK4
Show all »
Show » Show » 146 16.4 No 0
ACAD10-014 ENSP00000446711
ENST00000507683
Show » Show » 278 31 No 0
ACAD10-018 ENSP00000446959
ENST00000549590
F8W1I9
Show all »
Show » Show » 710 80.5 No 0
ACAD10-019 ENSP00000446998
ENST00000552965
Show » 13 1.6 No 0