CD83

GENERAL INFORMATION

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Gene name

CD83

Gene description

CD83 molecule

Protein class

CD markers
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (bone marrow)
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in a subset of leukocytes.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA041454 , CAB002509
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (bone marrow)

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

CD83 (HGNC Symbol)

Synonyms

BL11, HB15

Description

CD83 molecule (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Chromosome

6

Cytoband

p23

Chromosome location (bp)

14117256 - 14136918

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112149 (version 78.38)

Entrez gene

9308

UniProt

Q01151 (UniProt - Evidence at protein level)

neXtProt

NX_Q01151

Antibodypedia

CD83 antibodies


PROTEIN BROWSER

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ENST00000379153
 
ENST00000612003
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD83-001 ENSP00000368450
ENST00000379153
Q01151
Show all »
Show » Show » 205 23 Yes 1
CD83-201 ENSP00000480760
ENST00000612003
Show » 146 16.6 No 1