C7

GENERAL INFORMATION

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Gene name

C7

Gene description

Complement component 7

Protein class

Cancer-related genes
Disease related genes
Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (adrenal gland)
GTEx:Tissue enhanced (ovary)

Protein evidence

Evidence at protein level

Protein localization

Liver, the gastrointestinal tract, cells in ductus seminiferous, seminal vesicle, renal tubuli, exocrine pancreas and most squamous epithelia showed moderate to strong cytoplasmic positivity. Most lymphoid tissues, muscle and cells in CNS were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA001465
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (adrenal gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (ovary)

Organ

Expression



GENE INFORMATION

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Gene name

C7

Synonyms

Description

Complement component 7 (HGNC Symbol)

Entrez gene summary

C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

p13.1

Chromosome location (bp)

40909252 - 40982939

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112936 (version 78.38)

Entrez gene

730

UniProt

P10643 (UniProt - Evidence at protein level)

neXtProt

NX_P10643

Antibodypedia

C7 antibodies


PROTEIN BROWSER

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ENST00000313164
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

C7-001 ENSP00000322061
ENST00000313164
P10643
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