UBE2B

GENERAL INFORMATION

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Gene name

UBE2B

Gene description

Ubiquitin-conjugating enzyme E2B

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

UBE2B (HGNC Symbol)

Synonyms

HHR6B, RAD6B, UBC2

Description

Ubiquitin-conjugating enzyme E2B (HGNC Symbol)

Entrez gene summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q31.1

Chromosome location (bp)

134371179 - 134391992

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000119048 (version 78.38)

Entrez gene

7320

UniProt

P63146 (UniProt - Evidence at protein level)

neXtProt

NX_P63146

Antibodypedia

UBE2B antibodies


PROTEIN BROWSER

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ENST00000265339
 
ENST00000506787
 
ENST00000507277
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBE2B-001 ENSP00000265339
ENST00000265339
P63146
Show all »
Show » Show » 152 17.3 No 0
UBE2B-005 ENSP00000426364
ENST00000506787
H0YA80
Show all »
Show » Show » 138 15.4 No 0
UBE2B-008 ENSP00000425137
ENST00000507277
Show » 141 16.1 No 0