CANX

GENERAL INFORMATION

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Gene name

CANX

Gene description

Calnexin

Protein class

Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Intracellular,Membrane,Secreted

Number of transcripts

13
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA009433 , HPA009696 , CAB004738
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

CANX (HGNC Symbol)

Synonyms

CNX, IP90, P90

Description

Calnexin (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q35.3

Chromosome location (bp)

179678628 - 179730925

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000127022 (version 78.38)

Entrez gene

821

UniProt

P27824 (UniProt - Evidence at protein level)

neXtProt

NX_P27824

Antibodypedia

CANX antibodies


PROTEIN BROWSER

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ENST00000247461
 
ENST00000452673
 
ENST00000502296
 
ENST00000502498
 
ENST00000502673
 
ENST00000504734
 
ENST00000506654
 
ENST00000507307
 
ENST00000508787
 
ENST00000509563
 
ENST00000510810
 
ENST00000513246
 
ENST00000514383
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CANX-001 ENSP00000247461
ENST00000247461
P27824
Show all »
Show » Show » 592 67.6 Yes 1
CANX-002 ENSP00000424063
ENST00000504734
P27824
Show all »
Show » Show » 592 67.6 Yes 1
CANX-003 ENSP00000421107
ENST00000502673
D6RGY2
Show all »
Show » Show » 308 35.2 Yes 0
CANX-005 ENSP00000391646
ENST00000452673
P27824
Show all »
Show » Show » 592 67.6 Yes 1
CANX-006 ENSP00000424745
ENST00000502296
D6RAU8
Show all »
Show » Show » 134 14.8 Yes 0
CANX-007 ENSP00000425246
ENST00000502498
D6RDP7
Show all »
Show » Show » 168 18.7 Yes 0
CANX-008 ENSP00000426052
ENST00000507307
D6RHJ3
Show all »
Show » Show » 79 8.6 Yes 0
CANX-009 ENSP00000421813
ENST00000513246
D6RAQ8
Show all »
Show » Show » 107 11.9 Yes 0
CANX-010 ENSP00000421434
ENST00000509563
D6RFW4
Show all »
Show » 32 3.6 Yes 0
CANX-014 ENSP00000424140
ENST00000508787
Show » Show » 190 21.4 No 0
CANX-017 ENSP00000426555
ENST00000506654
D6RFL1
Show all »
Show » Show » 131 15.2 No 0
CANX-018 ENSP00000424740
ENST00000510810
Show » Show » 170 18.7 No 0
CANX-021 ENSP00000424341
ENST00000514383
D6RB85
Show all »
Show » Show » 144 16 Yes 0