ADCY4

GENERAL INFORMATION

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Gene name

ADCY4

Gene description

Adenylate cyclase 4

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA048344 , CAB005070
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ADCY4 (HGNC Symbol)

Synonyms

AC4

Description

Adenylate cyclase 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]

Chromosome

14

Cytoband

q12

Chromosome location (bp)

24318349 - 24335093

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129467 (version 78.38)

Entrez gene

196883

UniProt

Q8NFM4 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NFM4

Antibodypedia

ADCY4 antibodies


PROTEIN BROWSER

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ENST00000310677
 
ENST00000418030
 
ENST00000554068
 
ENST00000556932
 
ENST00000559167
 
ENST00000561138
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADCY4-001 ENSP00000312126
ENST00000310677
Q8NFM4
Show all »
Show » Show » 1077 119.8 No >9
ADCY4-002 ENSP00000452250
ENST00000554068
Q8NFM4
Show all »
Show » Show » 1077 119.8 No >9
ADCY4-006 ENSP00000393177
ENST00000418030
Q8NFM4
Show all »
Show » Show » 1077 119.8 No >9
ADCY4-011 ENSP00000450843
ENST00000556932
Show » Show » 137 15 No 0
ADCY4-016 ENSP00000453893
ENST00000561138
H0YN72
Show all »
Show » 115 12.5 No 2
ADCY4-019 ENSP00000453259
ENST00000559167
H0YLM0
Show all »
Show » 36 3.7 No 0