FGF13

GENERAL INFORMATION

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Gene name

FGF13

Gene description

Fibroblast growth factor 13

Protein class

Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enhanced (cerebral cortex, hippocampus)

Protein evidence

Evidence at protein level

Protein localization

Most glandular cells in the gastrointestinal tract, lymphoid tissues and glial cells in CNS showed strong cytoplasmic positivity. Adipocytes, placental trophoblasts, salivary gland and skin displayed moderate to strong cytoplasmic positivity. Remaining normal tissues were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA002809
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Hippocampus

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, hippocampus)

Organ

Expression



GENE INFORMATION

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Gene name

FGF13 (HGNC Symbol)

Synonyms

FGF2, FHF2

Description

Fibroblast growth factor 13 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]

Chromosome

X

Cytoband

Chromosome location (bp)

138631574 - 139222777

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129682 (version 78.38)

Entrez gene

2258

UniProt

Q92913 (UniProt - Evidence at protein level)

neXtProt

NX_Q92913

Antibodypedia

FGF13 antibodies


PROTEIN BROWSER

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ENST00000305414
 
ENST00000315930
 
ENST00000421460
 
ENST00000436198
 
ENST00000441825
 
ENST00000448673
 
ENST00000455663
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF13-001 ENSP00000322390
ENST00000315930
Q92913
Show all »
Show » Show » 245 27.6 No 0
FGF13-002 ENSP00000303391
ENST00000305414
Q92913
Show all »
Show » Show » 192 21.6 No 0
FGF13-003 ENSP00000396198
ENST00000436198
B1AK17
Show all »
Show » Show » 221 25.3 No 0
FGF13-004 ENSP00000411999
ENST00000448673
B1B1H9
Show all »
Show » Show » 98 11.2 No 0
FGF13-005 ENSP00000406916
ENST00000455663
B1AJW0
Show all »
Show » Show » 207 23.7 No 0
FGF13-006 ENSP00000388688
ENST00000421460
Q92913
Show all »
Show » Show » 43 5.1 No 0
FGF13-201 ENSP00000409276
ENST00000441825
Q92913
Show all »
Show » Show » 226 25.6 No 0