SHC2

GENERAL INFORMATION

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Gene name

SHC2

Gene description

SHC (Src homology 2 domain containing) transforming protein 2

Protein class

Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Normal tissues were in general moderately to strongly stained in cytoplasm. Strongest staining was observed in exocrine glandular cells, the gastro-intestinal tract, trophoblastic cells and urinary bladder. Lymphoid tissues were in general weakly stained. In a few neuronal cells, additional nucleolar staining was found.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA006136
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SHC2 (HGNC Symbol)

Synonyms

SCK, SHCB, SLI

Description

SHC (Src homology 2 domain containing) transforming protein 2 (HGNC Symbol)

Entrez gene summary

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

416583 - 460996

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129946 (version 78.38)

Entrez gene

25759

UniProt

P98077 (UniProt - Evidence at protein level)

neXtProt

NX_P98077

Antibodypedia

SHC2 antibodies


PROTEIN BROWSER

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ENST00000264554
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SHC2-001 ENSP00000264554
ENST00000264554
P98077
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