RHPN2

GENERAL INFORMATION

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Gene name

RHPN2

Gene description

Rhophilin, Rho GTPase binding protein 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues displayed weak to moderate cytoplasmic and nuclear positivity. Squamous epithelial cells, thyroid, adrenal gland, myoepithelial cells of breast, neuronal cells, hematopoietic cells and smooth muscle cells were strongly stained. Pneumocytes, renal glomeruli and most mesenchymal cells were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA051749
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Thyroid gland

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

RHPN2

Synonyms

Description

Rhophilin, Rho GTPase binding protein 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]

Chromosome

19

Cytoband

q13.11

Chromosome location (bp)

32978593 - 33064888

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131941 (version 78.38)

Entrez gene

85415

UniProt

Q8IUC4 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IUC4

Antibodypedia

RHPN2 antibodies


PROTEIN BROWSER

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ENST00000254260
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RHPN2-001 ENSP00000254260
ENST00000254260
Q8IUC4
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