TRIM22

GENERAL INFORMATION

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Gene name

TRIM22

Gene description

Tripartite motif containing 22

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Nuclear and cytoplasmic expression in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA003307 , HPA003575
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

TRIM22 (HGNC Symbol)

Synonyms

GPSTAF50, RNF94, STAF50

Description

Tripartite motif containing 22 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Chromosome

11

Cytoband

p15.4

Chromosome location (bp)

5689689 - 5737089

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000132274 (version 78.38)

Entrez gene

10346

UniProt

Q8IYM9 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IYM9

Antibodypedia

TRIM22 antibodies


PROTEIN BROWSER

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ENST00000379965
 
ENST00000414641
 
ENST00000425490
 
ENST00000429063
 
ENST00000444844
 
ENST00000450670
 
ENST00000454828
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRIM22-001 ENSP00000369299
ENST00000379965
Q8IYM9
Show all »
Show » Show » 498 56.9 No 0
TRIM22-003 ENSP00000400417
ENST00000425490
C9J060
Show all »
Show » Show » 203 23.7 No 0
TRIM22-005 ENSP00000396849
ENST00000414641
C9JIU5
Show all »
Show » Show » 227 26.3 No 0
TRIM22-006 ENSP00000393250
ENST00000454828
C9JWC5
Show all »
Show » Show » 305 34.9 No 0
TRIM22-008 ENSP00000406412
ENST00000450670
H7C2K0
Show all »
Show » 63 7.6 No 0
TRIM22-010 ENSP00000409991
ENST00000429063
Show » 37 4.3 No 0
TRIM22-011 ENSP00000404204
ENST00000444844
Show » 38 4.4 No 0