KCNK1

GENERAL INFORMATION

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Gene name

KCNK1

Gene description

Potassium channel, subfamily K, member 1

Protein class

Predicted membrane proteins
Voltage-gated ion channels

Predicted localization

Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enhanced (cerebellum)

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression at variable levels.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA016049 , CAB022588
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebellum)

Organ

Expression



GENE INFORMATION

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Gene name

KCNK1 (HGNC Symbol)

Synonyms

DPK, K2p1.1, TWIK-1

Description

Potassium channel, subfamily K, member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q42.2

Chromosome location (bp)

233614004 - 233672512

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135750 (version 78.38)

Entrez gene

3775

UniProt

O00180 (UniProt - Evidence at protein level)

neXtProt

NX_O00180

Antibodypedia

KCNK1 antibodies


PROTEIN BROWSER

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ENST00000366621
 
ENST00000446915
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNK1-001 ENSP00000355580
ENST00000366621
O00180
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Show » Show » 336 38.1 No 6
KCNK1-006 ENSP00000409626
ENST00000446915
Q5T5E6
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Show » Show » 242 27.5 No 4