CEP350

GENERAL INFORMATION

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Gene name

CEP350

Gene description

Centrosomal protein 350kDa

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA028355 , HPA028357
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

CEP350 (HGNC Symbol)

Synonyms

CAP350, KIAA0480

Description

Centrosomal protein 350kDa (HGNC Symbol)

Entrez gene summary

The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q25.2

Chromosome location (bp)

179954738 - 180114880

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135837 (version 78.38)

Entrez gene

9857

UniProt

Q5VT06 (UniProt - Evidence at protein level)

neXtProt

NX_Q5VT06

Antibodypedia

CEP350 antibodies


PROTEIN BROWSER

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ENST00000357434
 
ENST00000367607
 
ENST00000417046
 
ENST00000418229
 
ENST00000429851
 
ENST00000437245
 
ENST00000491495
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CEP350-001 ENSP00000356579
ENST00000367607
Q5VT06
Show all »
Show » Show » 3117 350.9 No 0
CEP350-004 ENSP00000409395
ENST00000437245
Q5T2X5
Show all »
Show » Show » 110 12.6 No 0
CEP350-005 ENSP00000401608
ENST00000417046
Q5T2X4
Show all »
Show » Show » 581 66.8 No 0
CEP350-007 ENSP00000412460
ENST00000429851
Q5T2X4
Show all »
Show » Show » 1292 147.2 No 0
CEP350-008 ENSP00000407044
ENST00000418229
Show » 331 36.8 No 0
CEP350-011 ENSP00000350016
ENST00000357434
A2A4F6
Show all »
Show » Show » 130 14.6 No 0
CEP350-012 ENSP00000435808
ENST00000491495
E9PIK0
Show all »
Show » Show » 242 27.5 No 0