MTCH1

GENERAL INFORMATION

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Gene name

MTCH1

Gene description

Mitochondrial carrier 1

Protein class

Mitochondrial proteins
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General granular cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA015971
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MTCH1 (HGNC Symbol)

Synonyms

CGI-64, PSAP, SLC25A49

Description

Mitochondrial carrier 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]

Chromosome

6

Cytoband

p21.2

Chromosome location (bp)

36968141 - 36986298

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137409 (version 78.38)

Entrez gene

23787

UniProt

Q9NZJ7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NZJ7

Antibodypedia

MTCH1 antibodies


PROTEIN BROWSER

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ENST00000373616
 
ENST00000373627
 
ENST00000418541
 
ENST00000460219
 
ENST00000538808
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MTCH1-001 ENSP00000362718
ENST00000373616
Q9NZJ7
Show all »
Show » Show » 372 39.9 No 2
MTCH1-003 ENSP00000399187
ENST00000418541
Show » 201 21.3 No 2
MTCH1-005 ENSP00000419739
ENST00000460219
H0Y8C3
Show all »
Show » Show » 394 43.1 No 3
MTCH1-008 ENSP00000362730
ENST00000373627
Q9NZJ7
Show all »
Show » Show » 389 41.5 No 2
MTCH1-201 ENSP00000437660
ENST00000538808
Show » 363 40 No 3