AWAT2

GENERAL INFORMATION

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Gene name

AWAT2

Gene description

Acyl-CoA wax alcohol acyltransferase 2

Protein class

Enzymes
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (skin)
GTEx:Group enriched (skin)

Protein evidence

Evidence at protein level

Protein localization

External data suggests expression in sebaceous glands. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded. Pending additional tissues.

Data reliability

Uncertain based on 1 antibody.
HPA062748
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (skin)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (skin)

Organ

Expression



GENE INFORMATION

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Gene name

AWAT2 (HGNC Symbol)

Synonyms

DGAT2L4, MFAT

Description

Acyl-CoA wax alcohol acyltransferase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010]

Chromosome

X

Cytoband

q13.1

Chromosome location (bp)

70040542 - 70049938

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147160 (version 78.38)

Entrez gene

158835

UniProt

Q6E213 (UniProt - Evidence at protein level)

neXtProt

NX_Q6E213

Antibodypedia

AWAT2 antibodies


PROTEIN BROWSER

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ENST00000276101
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AWAT2-001 ENSP00000421172
ENST00000276101
Q6E213
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