SAP18

GENERAL INFORMATION

? »

Gene name

SAP18

Gene description

Sin3A-associated protein, 18kDa

Protein class

Predicted intracellular proteins
Transporters

Predicted localization

Intracellular

Number of transcripts

6
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear expression.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA011352 , CAB012273
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

SAP18 (HGNC Symbol)

Synonyms

2HOR0202, MGC27131, SAP18p

Description

Sin3A-associated protein, 18kDa (HGNC Symbol)

Entrez gene summary

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2008]

Chromosome

13

Cytoband

q12.11

Chromosome location (bp)

21140514 - 21149084

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000150459 (version 78.38)

Entrez gene

10284

UniProt

O00422 (UniProt - Evidence at protein level)

neXtProt

NX_O00422

Antibodypedia

SAP18 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000382533
 
ENST00000450573
 
ENST00000467636
 
ENST00000492245
 
ENST00000607003
 
ENST00000621421
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SAP18-001 ENSP00000371973
ENST00000382533
X6RAL5
Show all »
Show » Show » 172 19.5 No 0
SAP18-005 ENSP00000475358
ENST00000467636
U3KPY7
Show all »
Show » 78 9.1 No 0
SAP18-006 ENSP00000475435
ENST00000492245
Show » 59 6.8 No 0
SAP18-008 ENSP00000391846
ENST00000450573
H7BZW6
Show all »
Show » Show » 143 16 No 0
SAP18-009 ENSP00000475925
ENST00000607003
O00422
Show all »
Show » Show » 153 17.6 No 0
SAP18-201 ENSP00000481842
ENST00000621421
X6RAL5
Show all »
Show » Show » 172 19.5 No 0