GPR78

GENERAL INFORMATION

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Gene name

GPR78

Gene description

G protein-coupled receptor 78

Protein class

G-protein coupled receptors
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Not detected
GTEx:Tissue enhanced (esophagus, vagina)

Protein evidence

Evidence at protein level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

No RNA expression data detected and pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA013209
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Not detected

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (esophagus, vagina)

Organ

Expression



GENE INFORMATION

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Gene name

GPR78

Synonyms

Description

G protein-coupled receptor 78 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]

Chromosome

4

Cytoband

p16.1

Chromosome location (bp)

8558725 - 8619761

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000155269 (version 78.38)

Entrez gene

27201

UniProt

Q96P69 (UniProt - Evidence at protein level)

neXtProt

NX_Q96P69

Antibodypedia

GPR78 antibodies


PROTEIN BROWSER

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ENST00000382487
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPR78-005 ENSP00000371927
ENST00000382487
Q96P69
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